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Kerangueven F, Noguchi T, Wargniez V, et al. Multiple sites of loss of heterozygosity on chromosome arms 3p and 3q in human breast carcinomas. Oncol Rep. 1996;3(2):313-6doi: 10.3892/or.3.2.313.
Kerangueven, F., Noguchi, T., Wargniez, V., Allione, F., Geneix, J., Jacquemier, J., Theillet, C., Sobol, H., & Birnbaum, D. (1996). Multiple sites of loss of heterozygosity on chromosome arms 3p and 3q in human breast carcinomas. Oncology reports, 3(2), 313-6. https://doi.org/10.3892/or.3.2.313
Kerangueven, F, et al. "Multiple sites of loss of heterozygosity on chromosome arms 3p and 3q in human breast carcinomas." Oncology reports vol. 3,2 (1996): 313-6. doi: https://doi.org/10.3892/or.3.2.313
Kerangueven F, Noguchi T, Wargniez V, Allione F, Geneix J, Jacquemier J, Theillet C, Sobol H, Birnbaum D. Multiple sites of loss of heterozygosity on chromosome arms 3p and 3q in human breast carcinomas. Oncol Rep. 1996 Mar;3(2):313-6. doi: 10.3892/or.3.2.313. PMID: 21594365.
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Oncol Rep. 1996 Mar;3(2):313-6. doi: 10.3892/or.3.2.313.

Multiple sites of loss of heterozygosity on chromosome arms 3p and 3q in human breast carcinomas.

Oncology reports

F Kerangueven, T Noguchi, V Wargniez, F Allione, J Geneix, J Jacquemier, C Theillet, H Sobol, D Birnbaum

Affiliations

  1. U119 INSERM,F-13009 MARSEILLE,FRANCE. INST J PAOLI I CALMETTES,LAB BIOL TUMEURS,F-13009 MARSEILLE,FRANCE. INST J PAOLI I CALMETTES,DEPT NUCL MED,F-13009 MARSEILLE,FRANCE. INST J PAOLI I CALMETTES,DEPT ANATOMOPATHOL,F-13009 MARSEILLE,FRANCE. INST J PAOLI I CALMETTES,DEPT ONCOGENET,F-13009 MARSEILLE,FRANCE. CNRS URA 1191,MONTPELLIER,FRANCE.

PMID: 21594365 DOI: 10.3892/or.3.2.313

Abstract

Loss of heterozygosity (LOH) at loci from both arms of chromosome 3 were shown to occur in a high proportion of breast carcinomas. Six regions of consistent loss were identified, and were variably involved in the tumors. This suggests that multiple potential tumor suppressor genes involved in mammary carcinogenesis are present on chromosome 3.

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