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Relakis K, Cardamakis E, Korantzis A, et al. Treatment of flat or accuminata condylomata of the female genital tract with interferon alpha-2 alpha. Oncol Rep. 1996;3(5):951-5doi: 10.3892/or.3.5.951.
Relakis, K., Cardamakis, E., Korantzis, A., Kotoulas, I., Stathopoulos, E., Metalinos, K., Papathanasiou, Z., Mantouvalos, H., Tzingounis, V., & Koumantakis, E. (1996). Treatment of flat or accuminata condylomata of the female genital tract with interferon alpha-2 alpha. Oncology reports, 3(5), 951-5. https://doi.org/10.3892/or.3.5.951
Relakis, K, et al. "Treatment of flat or accuminata condylomata of the female genital tract with interferon alpha-2 alpha." Oncology reports vol. 3,5 (1996): 951-5. doi: https://doi.org/10.3892/or.3.5.951
Relakis K, Cardamakis E, Korantzis A, Kotoulas I, Stathopoulos E, Metalinos K, Papathanasiou Z, Mantouvalos H, Tzingounis V, Koumantakis E. Treatment of flat or accuminata condylomata of the female genital tract with interferon alpha-2 alpha. Oncol Rep. 1996 Sep;3(5):951-5. doi: 10.3892/or.3.5.951. PMID: 21594489.
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Oncol Rep. 1996 Sep;3(5):951-5. doi: 10.3892/or.3.5.951.

Treatment of flat or accuminata condylomata of the female genital tract with interferon alpha-2 alpha.

Oncology reports

K Relakis, E Cardamakis, A Korantzis, I Kotoulas, E Stathopoulos, K Metalinos, Z Papathanasiou, H Mantouvalos, V Tzingounis, E Koumantakis

Affiliations

  1. UNIV HERAKLION,DEPT OBSTET & GYNECOL,IRAKLION,GREECE. UNIV PATRAS,DEPT OBSTET & GYNECOL,PATRAS,GREECE. EUROMED MED INST,ATHENS,GREECE. H VENIZELOU MATERN HOSP,DEPT OBSTET & GYNECOL 4,ATHENS,GREECE. ATHENS NAVAL HOSP,DEPT PATHOL,ATHENS,GREECE.

PMID: 21594489 DOI: 10.3892/or.3.5.951

Abstract

This study was undertaken to assess the effectiveness of Interferon administered parenterally in the treatment of flat or accuminata condylomata of the female genital tract. One hundred and forty-three women with condylomata were treated with CO2 laser vaporization, 5-FU topical application and interferon alpha-2 alpha (IFN alpha-2 alpha) parenterally. The cure rates in the various treatment groups were analysed by the chi-square test. The cure rates of the treatments used in the patients with condylomata accuminata were similar (p>0.1). The best cure rate for flat condylomata was achieved with the combination of CO2 laser vaporization plus 5-FU plus IFN alpha-2 alpha (high dose) (p<0.01). In conclusion, Interferon can be used as adjuvant treatment in patients with recalcitrant condylomata accuminata and as first line treatment in combination with 5-FU and CO2 laser vaporization in patients with flat condylomata.

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