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Sasson NJ, Pinkham AE, Carpenter KL, et al. The benefit of directly comparing autism and schizophrenia for revealing mechanisms of social cognitive impairment. J Neurodev Disord. 2010;3(2):87-100doi: 10.1007/s11689-010-9068-x.
Sasson, N. J., Pinkham, A. E., Carpenter, K. L., & Belger, A. (2011). The benefit of directly comparing autism and schizophrenia for revealing mechanisms of social cognitive impairment. Journal of neurodevelopmental disorders, 3(2), 87-100. https://doi.org/10.1007/s11689-010-9068-x
Sasson, Noah J, et al. "The benefit of directly comparing autism and schizophrenia for revealing mechanisms of social cognitive impairment." Journal of neurodevelopmental disorders vol. 3,2 (2011): 87-100. doi: https://doi.org/10.1007/s11689-010-9068-x
Sasson NJ, Pinkham AE, Carpenter KL, Belger A. The benefit of directly comparing autism and schizophrenia for revealing mechanisms of social cognitive impairment. J Neurodev Disord. 2011 Jun;3(2):87-100. doi: 10.1007/s11689-010-9068-x. Epub 2010 Dec 16. PMID: 21484194; PMCID: PMC3188289.
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J Neurodev Disord. 2011 Jun;3(2):87-100. doi: 10.1007/s11689-010-9068-x. Epub 2010 Dec 16.

The benefit of directly comparing autism and schizophrenia for revealing mechanisms of social cognitive impairment.

Journal of neurodevelopmental disorders

Noah J Sasson, Amy E Pinkham, Kimberly L H Carpenter, Aysenil Belger

Affiliations

  1. School of Behavioral and Brain Sciences, University of Texas at Dallas, GR41, 800 W. Campbell Rd, Richardson, TX, 75080, USA, [email protected].

PMID: 21484194 PMCID: PMC3188289 DOI: 10.1007/s11689-010-9068-x

Abstract

Autism and schizophrenia share a history of diagnostic conflation that was not definitively resolved until the publication of the DSM-III in 1980. Though now recognized as heterogeneous disorders with distinct developmental trajectories and dissociative features, much of the early nosological confusion stemmed from apparent overlap in certain areas of social dysfunction. In more recent years, separate but substantial literatures have accumulated for autism and schizophrenia demonstrating that abnormalities in social cognition directly contribute to the characteristic social deficits of both disorders. The current paper argues that direct comparison of social cognitive impairment can highlight shared and divergent mechanisms underlying pathways to social dysfunction, a process that can provide significant clinical benefit by informing the development of tailored treatment efforts. Thus, while the history of diagnostic conflation between autism and schizophrenia may have originated in similarities in social dysfunction, the goal of direct comparisons is not to conflate them once again but rather to reveal distinctions that illuminate disorder-specific mechanisms and pathways that contribute to social cognitive impairment.

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