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Zhang GF, Ma Z, Yang XH. 3-(2-Hydroxy-ethyl)-2-(p-tolyl-amino)-quinazolin-4(3H)-one. Acta Crystallogr Sect E Struct Rep Online. 2008;65:o34-5doi: 10.1107/S1600536808040440.
Zhang, G. F., Ma, Z., & Yang, X. H. (2008). 3-(2-Hydroxy-ethyl)-2-(p-tolyl-amino)-quinazolin-4(3H)-one. Acta crystallographica. Section E, Structure reports online, 65o34-5. https://doi.org/10.1107/S1600536808040440
Zhang, Gui-Fu, et al. "3-(2-Hydroxy-ethyl)-2-(p-tolyl-amino)-quinazolin-4(3H)-one." Acta crystallographica. Section E, Structure reports online vol. 65 (2008): o34-5. doi: https://doi.org/10.1107/S1600536808040440
Zhang GF, Ma Z, Yang XH. 3-(2-Hydroxy-ethyl)-2-(p-tolyl-amino)-quinazolin-4(3H)-one. Acta Crystallogr Sect E Struct Rep Online. 2008 Dec 06;65:o34-5. doi: 10.1107/S1600536808040440. PMID: 21581677; PMCID: PMC2967952.
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Acta Crystallogr Sect E Struct Rep Online. 2008 Dec 06;65:o34-5. doi: 10.1107/S1600536808040440.

3-(2-Hydroxy-ethyl)-2-(p-tolyl-amino)-quinazolin-4(3H)-one.

Acta crystallographica. Section E, Structure reports online

Gui-Fu Zhang, Zuan Ma, Xu-Hong Yang

PMID: 21581677 PMCID: PMC2967952 DOI: 10.1107/S1600536808040440

Abstract

In the title compound, C(17)H(17)N(3)O(2), the quinazolinone ring system is essentially planar. The benzene ring is twisted with respect to it by a dihedral angle of 32.7 (5)°. The mol-ecular conformation is stabilized by an N-H⋯O hydrogen bond, and the crystal structure is stabilized by inter-molecular O-H⋯N inter-actions.

References

  1. Pharmazie. 1997 Mar;52(3):189-94 - PubMed
  2. Acta Crystallogr Sect E Struct Rep Online. 2007 Dec 06;64(Pt 1):o137 - PubMed
  3. Acta Crystallogr Sect E Struct Rep Online. 2008 Jan 30;64(Pt 2):o535 - PubMed
  4. J Med Chem. 2002 Jul 4;45(14):3057-66 - PubMed
  5. J Med Chem. 1999 Nov 4;42(22):4705-13 - PubMed
  6. J Med Chem. 1997 May 9;40(10):1519-29 - PubMed
  7. Acta Crystallogr Sect E Struct Rep Online. 2007 Dec 21;64(Pt 1):o311-2 - PubMed
  8. J Med Chem. 1998 May 21;41(11):1869-82 - PubMed
  9. J Med Chem. 1991 Apr;34(4):1492-503 - PubMed
  10. Pharm Acta Helv. 1999 Dec;74(1):11-7 - PubMed
  11. J Med Chem. 2001 Aug 16;44(17):2719-34 - PubMed
  12. Acta Crystallogr A. 2008 Jan;64(Pt 1):112-22 - PubMed

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