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Yang HZ, Gao HT, Yang XH. 3,3'-Bis(4-chloro-phen-yl)-2,2'-(m-phenyl-enedi-oxy)diquinazolin-4(3H)-one. Acta Crystallogr Sect E Struct Rep Online. 2008;65:o59-60doi: 10.1107/S1600536808040567.
Yang, H. Z., Gao, H. T., & Yang, X. H. (2008). 3,3'-Bis(4-chloro-phen-yl)-2,2'-(m-phenyl-enedi-oxy)diquinazolin-4(3H)-one. Acta crystallographica. Section E, Structure reports online, 65o59-60. https://doi.org/10.1107/S1600536808040567
Yang, Hai-Zhou, et al. "3,3'-Bis(4-chloro-phen-yl)-2,2'-(m-phenyl-enedi-oxy)diquinazolin-4(3H)-one." Acta crystallographica. Section E, Structure reports online vol. 65 (2008): o59-60. doi: https://doi.org/10.1107/S1600536808040567
Yang HZ, Gao HT, Yang XH. 3,3'-Bis(4-chloro-phen-yl)-2,2'-(m-phenyl-enedi-oxy)diquinazolin-4(3H)-one. Acta Crystallogr Sect E Struct Rep Online. 2008 Dec 10;65:o59-60. doi: 10.1107/S1600536808040567. PMID: 21581700; PMCID: PMC2967973.
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Acta Crystallogr Sect E Struct Rep Online. 2008 Dec 10;65:o59-60. doi: 10.1107/S1600536808040567.

3,3'-Bis(4-chloro-phen-yl)-2,2'-(m-phenyl-enedi-oxy)diquinazolin-4(3H)-one.

Acta crystallographica. Section E, Structure reports online

Hai-Zhou Yang, Hai-Tao Gao, Xu-Hong Yang

PMID: 21581700 PMCID: PMC2967973 DOI: 10.1107/S1600536808040567

Abstract

In the title compound, C(34)H(20)Cl(2)N(4)O(4), the two quinazoline heterocyclic systems and the adjacent chloro-benzene rings are not coplanar, but oriented at dihedral angles of 66.66 (13) and 52.48 (12)°, respectively. The quinazoline ring systems are nearly planar, with dihedral angles between the planes of the two rings of 5.43 (16) and 3.40 (14)°, and are oriented at dihedral angles of 79.73 (13) and 83.52 (13)° with respect to the adjacent benzene ring between them. Inter-molecular C-H⋯O hydrogen bonds contribute to the stability of the structure. In addition, weak π-π stacking inter-actions [centroid-to-centroid distances = 3.872 (1) and 3.876 (1) Å] are observed in the crystal structure.

References

  1. Pharmazie. 1997 Mar;52(3):189-94 - PubMed
  2. Acta Crystallogr Sect E Struct Rep Online. 2007 Dec 06;64(Pt 1):o137 - PubMed
  3. Acta Crystallogr Sect E Struct Rep Online. 2008 Jan 30;64(Pt 2):o535 - PubMed
  4. J Med Chem. 2002 Jul 4;45(14):3057-66 - PubMed
  5. J Med Chem. 1999 Nov 4;42(22):4705-13 - PubMed
  6. J Med Chem. 1997 May 9;40(10):1519-29 - PubMed
  7. Acta Crystallogr Sect E Struct Rep Online. 2007 Dec 21;64(Pt 1):o311-2 - PubMed
  8. J Med Chem. 1998 May 21;41(11):1869-82 - PubMed
  9. J Med Chem. 1991 Apr;34(4):1492-503 - PubMed
  10. Pharm Acta Helv. 1999 Dec;74(1):11-7 - PubMed
  11. J Med Chem. 2001 Aug 16;44(17):2719-34 - PubMed
  12. Acta Crystallogr A. 2008 Jan;64(Pt 1):112-22 - PubMed

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