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Restor Neurol Neurosci. 1990 Jan 01;1(3):211-5. doi: 10.3233/RNN-1990-13406.

Insulin-like growth factor I (IGF-I) and regeneration of the sciatic nerve of the rat.

Restorative neurology and neuroscience

M Kanje, A Skottner, J Sjöberg

Affiliations

  1. Department of Zoophysiology, University of Lund, Lund (Sweden).

PMID: 21551558 DOI: 10.3233/RNN-1990-13406

Abstract

We have found that insulin-like growth factor I (IGF-I) stimulates regeneration of the rat sciatic nerve. This paper reviews and adds some new data to our investigations on the effects of local administration of IGF-I to the sciatic nerve after infliction of a crush or freeze injury.

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