Display options
Cite
Banga Singh KK, Ojha SC, Deris ZZ, et al. A 9-year study of shigellosis in Northeast Malaysia: Antimicrobial susceptibility and shifting species dominance. Z Gesundh Wiss. 2010;19(3):231-236doi: 10.1007/s10389-010-0384-0.
Banga Singh, K. K., Ojha, S. C., Deris, Z. Z., & Rahman, R. A. (2011). A 9-year study of shigellosis in Northeast Malaysia: Antimicrobial susceptibility and shifting species dominance. Zeitschrift fur Gesundheitswissenschaften = Journal of public health, 19(3), 231-236. https://doi.org/10.1007/s10389-010-0384-0
Banga Singh, Kirnpal-Kaur, et al. "A 9-year study of shigellosis in Northeast Malaysia: Antimicrobial susceptibility and shifting species dominance." Zeitschrift fur Gesundheitswissenschaften = Journal of public health vol. 19,3 (2011): 231-236. doi: https://doi.org/10.1007/s10389-010-0384-0
Banga Singh KK, Ojha SC, Deris ZZ, Rahman RA. A 9-year study of shigellosis in Northeast Malaysia: Antimicrobial susceptibility and shifting species dominance. Z Gesundh Wiss. 2011 Jun;19(3):231-236. doi: 10.1007/s10389-010-0384-0. Epub 2010 Nov 19. PMID: 21654922; PMCID: PMC3089725.
Copy Download .nbib Format: NLM
Share it on

Z Gesundh Wiss. 2011 Jun;19(3):231-236. doi: 10.1007/s10389-010-0384-0. Epub 2010 Nov 19.

A 9-year study of shigellosis in Northeast Malaysia: Antimicrobial susceptibility and shifting species dominance.

Zeitschrift fur Gesundheitswissenschaften = Journal of public health

Kirnpal-Kaur Banga Singh, Suvash Chandra Ojha, Zakuan Zainy Deris, Rosliza Abdul Rahman

PMID: 21654922 PMCID: PMC3089725 DOI: 10.1007/s10389-010-0384-0

Abstract

AIMS: In Malaysia, Shigella spp. is the third most common bacterial agent responsible for childhood diarrhoea. This study was conducted to determine the prevalence and antimicrobial susceptibility patterns of Shigella spp. isolated from patients admitted to the Hospital Universiti Sains Malaysia from January 2001 to December 2009. SUBJECTS AND METHODS: A hospital-based retrospective study was used. Stool samples from patients were cultured using a standard culture method. Shigella spp. isolates were identified by biochemical and serological methods, and the antimicrobial susceptibility pattern was evaluated using the Kirby-Bauer disc-diffusion method. RESULTS: A total of 138 Shigella spp. were isolated from a total of 14,830 routine stool specimens, yielding an isolation rate of 0.93% that corresponded to 9.99% of the 1,381 bacterial pathogens isolated. Of these isolates, S. sonnei was the predominant species, followed by S. flexneri and S. boydii. Seasonal variation was noticed, and no significant differences were detected in the demographic data for S. flexneri and S. sonnei. The susceptibility of all isolated Shigella strains was tested against seven antibiotics. Ceftriaxone (99.1%), ciprofloxacin (98.4%), and nalidixic acid (93.8%) were effective against the Shigella strains, whereas tetracycline and trimethoprim-sulfamethoxazole exhibited high frequencies of resistance (58.4% and 53.8%, respectively). CONCLUSION: This study is important for public health education aimed at reducing the morbidity and mortality associated with Shigella spp. infection. Our results also will be helpful for paediatricians and microbiologists in the selection of appropriate antibiotics for the management of diarrhoea.

References

  1. J Pak Med Assoc. 2005 May;55(5):184-8 - PubMed
  2. Indian J Pathol Microbiol. 1977 Jan;20(1):15-21 - PubMed
  3. Scand J Infect Dis. 1998;30(4):351-3 - PubMed
  4. Kansenshogaku Zasshi. 2000 Dec;74(12):1004-11 - PubMed
  5. J Infect. 2005 Oct;51(3):222-9 - PubMed
  6. J Microbiol Immunol Infect. 2008 Apr;41(2):107-11 - PubMed
  7. Epidemiol Infect. 2005 Dec;133(6):1089-95 - PubMed
  8. J Clin Microbiol. 2007 Feb;45(2):678-9 - PubMed
  9. Rev Infect Dis. 1991 Mar-Apr;13 Suppl 4:S245-51 - PubMed
  10. Jpn J Infect Dis. 2008 Jul;61(4):307-9 - PubMed
  11. J Clin Microbiol. 1995 Mar;33(3):609-14 - PubMed
  12. Curr Top Microbiol Immunol. 2002;264(1):49-65 - PubMed
  13. Jpn J Infect Dis. 2003 Feb;56(1):33-4 - PubMed
  14. Bull World Health Organ. 1999;77(8):651-66 - PubMed
  15. Int J Antimicrob Agents. 2002 Nov;20(5):387-9 - PubMed
  16. Appl Environ Microbiol. 2002 Aug;68(8):3908-13 - PubMed
  17. J Health Popul Nutr. 2003 Jun;21(2):96-102 - PubMed
  18. Antimicrob Agents Chemother. 2006 Jan;50(1):49-54 - PubMed
  19. Scand J Infect Dis. 1989;21(4):415-9 - PubMed
  20. Kathmandu Univ Med J (KUMJ). 2007 Jan-Mar;5(1):32-7 - PubMed
  21. Med J Malaysia. 2003 Jun;58(2):262-7 - PubMed
  22. Clin Infect Dis. 2000 Mar;30(3):515-9 - PubMed
  23. J Microbiol. 2005 Apr;43(2):133-43 - PubMed
  24. Crit Rev Food Sci Nutr. 2006;46(7):551-67 - PubMed
  25. Med J Malaysia. 2002 Mar;57(1):24-30 - PubMed
  26. J Health Popul Nutr. 2005 Dec;23(4):339-42 - PubMed
  27. Epidemiol Infect. 2004 Aug;132(4):579-83 - PubMed
  28. East Afr Med J. 1979 Aug;56(8):381-7 - PubMed
  29. Ann Trop Med Parasitol. 1996 Apr;90(2):105-14 - PubMed
  30. Am J Trop Med Hyg. 2005 Jun;72(6):851-4 - PubMed
  31. J Antimicrob Chemother. 2008 Jun;61(6):1315-8 - PubMed

Publication Types