Display options
Share it on

Sultan Qaboos Univ Med J. 2007 Apr;7(1):25-30.

Clinical and Epidemiological Characteristics of Pituitary Tumours using a Web-based Pituitary Tumour Registry in Oman.

Sultan Qaboos University medical journal

Abdullah Al-Futaisi, Al-Yaarubi Saif, Ibrahim Al-Zakwani, Salim Al-Qassabi, Shaden Al-Riyami, Yasser Wali

Affiliations

  1. Department of Medicine, Sultan Qaboos University, P. O. Box 35, Al-Khod 123, Sultanate of Oman.

PMID: 21654941 PMCID: PMC3086414

Abstract

OBJECTIVE: From a recently instituted web-based pituitary tumour registry at Sultan Qaboos University Hospital, Oman, this study explores the results of comprehensive clinical evaluation, hormonal levels, radiological evidence of pituitary mass lesion using magnetic resonance (MRI) and the different treatment modalities.

METHODS: All patients who were diagnosed with pituitary mass tumours in our tertiary care endocrinology clinic between January 1998 and February 2006 were registered in the Oman pituitary tumour registry. Two physicians performed hospital chart review and data entry.

RESULTS: A total of 160 entries were made into the pituitary tumour registry. The overall mean age of the cohort was 32 ±12 years (age range 8-73 years). The majority of registrations were female (n=114; 71%). There were 81 patients with non-functioning adenomas (50.6%), 59 with prolactinoma (36.9%) eight with acromegaly (5%), seven with craniopharyngioma (4.4%), four with Cushing's disease (2.5%) and one with sarcoidosis (0.6%). Sub-group analyses were done only for the subjects with the 3 most prevalent pituitary tumours (non-functioning adenomas, prolactinomas, and acromegaly). The most prevalent symptoms are amenorrhea-galactorrhea (n=55; 37%), headache (n=31; 21%) and fatigue (n=23; 16%). The most common treatment modality was medical (n=58; 39%), followed by observation (n=56; 38%), surgery (n=31; 21%) and surgery plus medical (n=3; 2%). None of the patients in this registry are recorded to have died.

CONCLUSION: To our knowledge, this is the first pituitary tumour registry in the Arabian Gulf countries using a web-based programme. This tumour registry will enable us to characterize clinical and the epidemiological features of pituitary tumours in the Sultanate of Oman.

Keywords: Clinical; Epidemiology; Oman; Pituitary adenomas; Registry

References

  1. Surg Neurol. 1996 Jul;46(1):28-31 - PubMed
  2. Ann Intern Med. 1990 Jun 15;112(12):925-31 - PubMed
  3. N Engl J Med. 1981 Jan 15;304(3):156-8 - PubMed
  4. Cancer. 1996 Aug 1;78(3):502-10 - PubMed
  5. Medicine (Baltimore). 1999 Jul;78(4):236-69 - PubMed
  6. Endocrinol Metab Clin North Am. 1997 Dec;26(4):725-40 - PubMed
  7. Mayo Clin Proc. 1978 Oct;53(10):641-3 - PubMed
  8. Ann Intern Med. 1994 May 15;120(10):817-20 - PubMed
  9. Ann N Y Acad Sci. 1982;381:6-16 - PubMed
  10. J Clin Endocrinol Metab. 1993 May;76(5):1089-94 - PubMed
  11. J Clin Endocrinol Metab. 2000 Jan;85(1):168-74 - PubMed
  12. Endocrinol Metab Clin North Am. 1999 Mar;28(1):81-117, vi - PubMed
  13. J Clin Endocrinol Metab. 1996 Oct;81(10):3455-9 - PubMed

Publication Types