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BMJ Case Rep. 2009;2009. doi: 10.1136/bcr.07.2008.0536. Epub 2009 Feb 26.

Metastatic osteosarcoma to the liver and the kidney: a case report and review of the literature.

BMJ case reports

Wen-Xi Yu, Yang Yao


  1. Medical College of Shanghai Jiaotong University, Oncology Deparment, Shanghai Sixth People's Hospital, No 600, Yi Shan Road, XuHui District, Shanghai 200233 China.

PMID: 21686756 PMCID: PMC3029436 DOI: 10.1136/bcr.07.2008.0536


Improvements in multimodal treatment for osteosarcoma, especially in the use of adjuvant chemotherapy, have increased event-free and overall survival. Meanwhile, the prolonged survival of patients has permitted the appearance of new, significant, extrapulmonary targets for metastasis. Here we report a middle-aged adult with osteosarcoma who developed hepatic and renal metastases 4 months after the diagnosis of osteosarcoma. Chemotherapy and radiofrequency ablation were performed. CT scan has shown that the metastatic lesion has stabilised in the liver and kidney in the latest follow-up. This suggests that early multimodal treatment may improve both the survival rate and the quality of life of osteosarcoma patients with extrapulmonary metastases.


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