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BMJ Case Rep. 2009;2009. doi: 10.1136/bcr.07.2008.0446. Epub 2009 Apr 28.

Multiple mononeuropathy following cocaine abuse.

BMJ case reports

Sándor Beniczky, Peer Tfelt-Hansen, Martin Fabricius, Kjeld V Andersen

Affiliations

  1. Department of Clinical Neurophysiology, Danish Epilepsy Canter, Visbys Allé 5, 4293 Dianalund.

PMID: 21686808 PMCID: PMC3029594 DOI: 10.1136/bcr.07.2008.0446

Abstract

A 31-year-old man with acute-onset of left-sided weakness following the sniffing of cocaine was admitted with rhabdomyolysis. Neurophysiological studies showed axonal degeneration in 4/10 sensory and 3/8 motor nerves, and conduction block outside the typical compression-sites in 3/8 motor nerves. The findings are consistent with a diagnosis of multiple mononeuropathy. Ischaemia due to vasoconstriction is currently believed to be the cause of muscle necrosis following cocaine abuse and we hypothesise that it also explains the neuropathy in this case.

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