Display options
Cite
Prajsnar A, Balak N, Walter GF, et al. Recurrent paraganglioma of Meckel's cave: Case report and a review of anatomic origin of paragangliomas. Surg Neurol Int. 2011;2:45doi: 10.4103/2152-7806.79763.
Prajsnar, A., Balak, N., Walter, G. F., Stan, A. C., Deinsberger, W., Tapul, L., & Bayindir, C. (2011). Recurrent paraganglioma of Meckel's cave: Case report and a review of anatomic origin of paragangliomas. Surgical neurology international, 245. https://doi.org/10.4103/2152-7806.79763
Prajsnar, Anna, et al. "Recurrent paraganglioma of Meckel's cave: Case report and a review of anatomic origin of paragangliomas." Surgical neurology international vol. 2 (2011): 45. doi: https://doi.org/10.4103/2152-7806.79763
Prajsnar A, Balak N, Walter GF, Stan AC, Deinsberger W, Tapul L, Bayindir C. Recurrent paraganglioma of Meckel's cave: Case report and a review of anatomic origin of paragangliomas. Surg Neurol Int. 2011;2:45. doi: 10.4103/2152-7806.79763. Epub 2011 Apr 19. PMID: 21660268; PMCID: PMC3108444.
Copy Download .nbib Format: NLM
Share it on

Surg Neurol Int. 2011;2:45. doi: 10.4103/2152-7806.79763. Epub 2011 Apr 19.

Recurrent paraganglioma of Meckel's cave: Case report and a review of anatomic origin of paragangliomas.

Surgical neurology international

Anna Prajsnar, Naci Balak, Gerhard F Walter, Alexandru C Stan, Wolfgang Deinsberger, Leyla Tapul, Cicek Bayindir

Affiliations

  1. Department of Neurosurgery, Klinikum Kassel, Kassel, Germany.

PMID: 21660268 PMCID: PMC3108444 DOI: 10.4103/2152-7806.79763

Abstract

BACKGROUND: Paragangliomas are rare, usually benign tumors of neural crest origin. They account for only 0.6% of all head and neck tumors. In the craniocervical area, they are more common in the carotid body and tympanico-jugular regions. To the authors' knowledge, a case of paraganglioma in Meckel's cave has not yet been reported in the medical literature. The pathogenesis and natural history of paragangliomas are still not well understood. We present a case of recurrent paraganglioma in Meckel's cave.

CASE DESCRIPTION: A 53-year-old woman was diagnosed with trigeminal neuralgia, dysesthesia and hypoesthesia on the left side of the face, hearing disturbance and a history of chronic, persistent temporal headaches. Magnetic resonance imaging (MRI) showed a lesion located in Meckel's cave on the left side, extending to the posterior cranial fossa and compressing the left cerebral peduncle. The lesion was first thought to be a recurrence of an atypical meningioma, as the pathologist described it in the tissue specimen resected 3 years earlier, and a decision for re-operation was made. A lateral suboccipital approach to the lesion was used under neuronavigational guidance. The tumor was removed, and histological examination proved the lesion to be a paraganglioma. Five months later, the follow-up MRI showed local regrowth, which required subsequent surgical intervention.

CONCLUSIONS: A paraganglioma in Meckel's cave is an uncommon tumor in this location. Although ectopic paragangliomas have been described in the literature, a paraganglioma atypically located in Meckel's cave makes a topographic correlation difficult, mainly because paraganglionic cells are usually not found in Meckel's cave. Another peculiarity of the case is the local recurrence of the tumor in a relatively short time despite an attempted, almost gross total resection.

Keywords: Intracranial tumors; Meckel's cave; neurocristopathies; paraganglioma; transmission electron microscopy

References

  1. Ultrastruct Pathol. 2001 May-Jun;25(3):201-6 - PubMed
  2. J Neurol. 1987 Oct;235(1):56-9 - PubMed
  3. Otolaryngol Head Neck Surg. 1988 Feb;98(2):150-4 - PubMed
  4. Neurosurgery. 2007 Sep;61(3 Suppl):15-23; discussion 23 - PubMed
  5. Cancer. 1999 Oct 15;86(8):1583-9 - PubMed
  6. Neurol Med Chir (Tokyo). 1999 Apr;39(4):308-12 - PubMed
  7. Arch Pathol Lab Med. 2000 Jun;124(6):877-9 - PubMed
  8. Isr Med Assoc J. 2002 Oct;4(10):829-31 - PubMed
  9. Head Neck. 2002 May;24(5):423-31 - PubMed
  10. Head Neck. 2010 Dec;32(12):1720-7 - PubMed
  11. Neurochirurgie. 2003 Nov;49(5):540-4 - PubMed
  12. Hum Pathol. 1987 Jul;18(7):715-27 - PubMed
  13. J Neurooncol. 2010 Mar;97(1):101-8 - PubMed
  14. Hum Pathol. 1979 Mar;10(2):191-218 - PubMed
  15. J Hypertens. 2008 Jul;26(7):1395-401 - PubMed
  16. Arch Pathol Lab Med. 1989 Nov;113(11):1209-18 - PubMed
  17. J Med Genet. 2008 Nov;45(11):689-94 - PubMed
  18. Neurosurgery. 2009 Mar;64(3 Suppl):ons71-82; discussion ons82-3 - PubMed
  19. J Craniofac Surg. 2010 Jan;21(1):117-20 - PubMed
  20. Zhonghua Bing Li Xue Za Zhi. 2008 Nov;37(11):765-7 - PubMed
  21. Neurol Sci. 2009 Dec;30(6):479-85 - PubMed
  22. Neurosurg Clin N Am. 2006 Apr;17(2):149-67, vii - PubMed
  23. J Neurosurg. 2006 Dec;105 Suppl:161-7 - PubMed
  24. J Neurosurg. 2005 Jan;102 Suppl:241-6 - PubMed
  25. Acta Neuropathol. 2007 Aug;114(2):97-109 - PubMed
  26. Clin Exp Otorhinolaryngol. 2009 Mar;2(1):28-32 - PubMed
  27. Neurosurg Focus. 2004 Aug 15;17(2):E4 - PubMed
  28. Skeletal Radiol. 1998 Feb;27(2):103-7 - PubMed
  29. Acta Neurochir Suppl. 2002;84:91-7 - PubMed
  30. Int J Radiat Oncol Biol Phys. 2006 Jul 15;65(4):1063-6 - PubMed
  31. Otolaryngol Head Neck Surg. 2009 May;140(5):724-9 - PubMed
  32. Rom J Morphol Embryol. 2009;50(4):613-7 - PubMed
  33. Otolaryngol Pol. 2010 Jun;64(7):65-72 - PubMed
  34. Otol Neurotol. 2005 Nov;26(6):1229-34 - PubMed
  35. Neurosurgery. 1989 May;24(5):762-4 - PubMed
  36. Acta Neurochir (Wien). 2006 Jan;148(1):63-6; discussion 66 - PubMed
  37. J Intern Med. 1991 Apr;229(4):371-3 - PubMed
  38. Clin Neuropathol. 2006 Sep-Oct;25(5):221-6 - PubMed
  39. Zh Vopr Neirokhir Im N N Burdenko. 1987 Sep-Oct;(5):8-15 - PubMed
  40. Eur J Vasc Endovasc Surg. 2008 Nov;36(5):517-9 - PubMed
  41. Clin Anat. 2005 Apr;18(3):210-4 - PubMed
  42. Acta Neurochir (Wien). 2000;142(9):1063-6 - PubMed
  43. Laryngoscope. 2000 Jan;110(1):35-8 - PubMed
  44. Neurosurg Focus. 2004 Aug 15;17(2):E11 - PubMed
  45. Otolaryngol Clin North Am. 2001 Oct;34(5):941-70, vii - PubMed
  46. Neurosurgery. 2006 Nov;59(5):1030-6; discussion 1036 - PubMed
  47. Cancer Res. 2009 Apr 15;69(8):3650-6 - PubMed
  48. Neurol India. 2008 Jan-Mar;56(1):57-61 - PubMed
  49. Am J Otol. 1993 Jul;14(4):398-402 - PubMed
  50. Am J Otolaryngol. 2007 Sep-Oct;28(5):347-9 - PubMed
  51. Head Neck. 2007 Aug;29(8):793-8 - PubMed
  52. Head Neck. 2008 Nov;30(11):1431-8 - PubMed
  53. Radiology. 1994 Jul;192(1):103-10 - PubMed
  54. Pediatr Pathol Lab Med. 1997 Jan-Feb;17(1):1-25 - PubMed
  55. Head Neck. 2002 Apr;24(4):332-8; discussion 338-9 - PubMed
  56. Skull Base Surg. 1999;9(3):185-94 - PubMed
  57. Stereotact Funct Neurosurg. 2009;87(1):31-6 - PubMed
  58. Oral Oncol. 2006 Nov;42(10):965-78 - PubMed
  59. J Clin Neurosci. 2008 Aug;15(8):937-9 - PubMed
  60. Cancer. 2003 Feb 15;97(4):1093-8 - PubMed
  61. Neurosurg Focus. 2004 Aug 15;17(2):E10 - PubMed
  62. Hum Pathol. 1989 Jan;20(1):29-39 - PubMed
  63. Endocr Pathol. 2006 Winter;17(4):337-44 - PubMed
  64. Neurosurgery. 1993 May;32(5):844-7 - PubMed
  65. Am J Otolaryngol. 2009 Jan-Feb;30(1):70; author reply 71 - PubMed
  66. Histopathology. 2009 May;54(6):775-7 - PubMed

Publication Types