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Anal Chem. 1999 Jul 01;71(13):2578-81. doi: 10.1021/ac981249q.

High-Speed TOFMS Detection for Capillary Electrophoresis.

Analytical chemistry

I M Lazar, A L Rockwood, E D Lee, J C Sin, M L Lee

Affiliations

  1. Sensar Corporation, 1662 West 820 North, Provo, Utah 84601, and Department of Chemistry and Biochemistry, Brigham Young University, Provo, Utah 84602.

PMID: 21662803 DOI: 10.1021/ac981249q

Abstract

A new, high-speed data acquisition system was tested for high storage rate time-of-flight mass spectrometry (TOFMS) detection in capillary electrophoresis (CE). For high spectral acquisition rates of 4 kHz, a spectral storage rate of 80 spectra s(-)(1) was achieved. The resulting detection limit was in the low amol range (10-25 amol) for continuous infusion investigations.

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