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Healy NA, Conneely JB, Mahon S, et al. Primary splenic lymphoma presenting with ascites. Rare Tumors. 2011;3(2):e25doi: 10.4081/rt.2011.e25.
Healy, N. A., Conneely, J. B., Mahon, S., O'Riardon, C., & McAnena, O. J. (2011). Primary splenic lymphoma presenting with ascites. Rare tumors, 3(2), e25. https://doi.org/10.4081/rt.2011.e25
Healy, Nuala A, et al. "Primary splenic lymphoma presenting with ascites." Rare tumors vol. 3,2 (2011): e25. doi: https://doi.org/10.4081/rt.2011.e25
Healy NA, Conneely JB, Mahon S, O'Riardon C, McAnena OJ. Primary splenic lymphoma presenting with ascites. Rare Tumors. 2011 Apr 04;3(2):e25. doi: 10.4081/rt.2011.e25. PMID: 21769324; PMCID: PMC3132129.
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Rare Tumors. 2011 Apr 04;3(2):e25. doi: 10.4081/rt.2011.e25.

Primary splenic lymphoma presenting with ascites.

Rare tumors

Nuala A Healy, John B Conneely, Sarah Mahon, Conor O'Riardon, Oliver J McAnena

Affiliations

  1. Department of Surgery, National University of Ireland, Galway;

PMID: 21769324 PMCID: PMC3132129 DOI: 10.4081/rt.2011.e25

Abstract

An 84 year-old gentleman presented with abdominal distension, anorexia and occasional epigastric pain over a four-week period. Blood parameters revealed a hypochromic microcytic anaemia. Both CT and US scan identified ascites and a mass in the left upper quadrant. An ascitic tap was performed identifying bloody ascites and the presence of reactive mesothelial cells on cytology. A subsequent laparotomy and splenectomy was performed. Histology of the resected spleen revealed a Grade 2 follicular lymphoma (Figure 2). The patient had an uneventful postoperative recovery and was well at 6 months follow up. The spleen is an organ with an important immunological function. Primary splenic involvement occurs in less than 1% of non-hodgkin's lymphoma. Symptoms of primary splenic lymphoma (PSL) include pyrexia, weight-loss, night sweats, generalised weakness and left upper quadrant pain secondary to spleno - megaly. Ascites is a rare presenting feature of PSL. This report illustrates a case of primary splenic lymphoma which poses diagnostic challenges for the pathologist and clinician and ultimately requires definitive splenectomy to confirm a diagnosis.Figure 2Photograph of histology slide displaying the lymphoma at 10× magnification.

Keywords: primary splenic lymphoma.

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