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Paran RD, Svobodová V. Effect of therapy by using advocate spot-on combination (imidacloprid 10% and moxidectin 2.5%) on subcutaneous dirofilariosis in dogs. Vet Med Int. 2011;2011:482746doi: 10.4061/2011/482746.
Paran, R. D., & Svobodová, V. (2011). Effect of therapy by using advocate spot-on combination (imidacloprid 10% and moxidectin 2.5%) on subcutaneous dirofilariosis in dogs. Veterinary medicine international, 2011482746. https://doi.org/10.4061/2011/482746
Paran, Radmila Dobešová, and Svobodová, Vlasta. "Effect of therapy by using advocate spot-on combination (imidacloprid 10% and moxidectin 2.5%) on subcutaneous dirofilariosis in dogs." Veterinary medicine international vol. 2011 (2011): 482746. doi: https://doi.org/10.4061/2011/482746
Paran RD, Svobodová V. Effect of therapy by using advocate spot-on combination (imidacloprid 10% and moxidectin 2.5%) on subcutaneous dirofilariosis in dogs. Vet Med Int. 2011;2011:482746. doi: 10.4061/2011/482746. Epub 2011 Jun 13. PMID: 21776349; PMCID: PMC3135109.
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Vet Med Int. 2011;2011:482746. doi: 10.4061/2011/482746. Epub 2011 Jun 13.

Effect of therapy by using advocate spot-on combination (imidacloprid 10% and moxidectin 2.5%) on subcutaneous dirofilariosis in dogs.

Veterinary medicine international

Radmila Dobešová Paran, Vlasta Svobodová

Affiliations

  1. Department of Parasitology, University of Veterinary and Pharmaceutical Sciences Brno, Palackého 1-3, 612 42 Brno, Czech Republic.

PMID: 21776349 PMCID: PMC3135109 DOI: 10.4061/2011/482746

Abstract

Dirofilaria (Nochtiella) repens is a filarioid parasite that causes subcutaneous dirofilariosis in dogs. Adults, while localized in subcutaneous tissues, lay embryos (microfilariae (mf)) into the blood stream of dogs, which constitute a reservoir for infection of other definitive or accidental hosts as humans. This study was carried out to assess the efficacy of spot-on combination of imidacloprid and moxidectin on microfilariaemia in naturally infected dogs. A group of 11 dogs was monthly examined for the presence of microfilariae in peripheral blood by modified Knott's test method. Treatment was administered monthly for 4 months. All dogs (i.e., 100%) became negative for microfilariaemia throughout the study. These results confirm the effect of the combination of imidacloprid and moxidectin on D. (Nochtiella) repens.

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