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Vyas HV, Eidem BW, Cetta F, et al. Myocardial tissue Doppler velocities in fetuses with hypoplastic left heart syndrome. Ann Pediatr Cardiol. 2011;4(2):129-34doi: 10.4103/0974-2069.84650.
Vyas, H. V., Eidem, B. W., Cetta, F., Acharya, G., Huhta, J., Roberson, D., & Cuneo, B. (2011). Myocardial tissue Doppler velocities in fetuses with hypoplastic left heart syndrome. Annals of pediatric cardiology, 4(2), 129-34. https://doi.org/10.4103/0974-2069.84650
Vyas, Himesh V, et al. "Myocardial tissue Doppler velocities in fetuses with hypoplastic left heart syndrome." Annals of pediatric cardiology vol. 4,2 (2011): 129-34. doi: https://doi.org/10.4103/0974-2069.84650
Vyas HV, Eidem BW, Cetta F, Acharya G, Huhta J, Roberson D, Cuneo B. Myocardial tissue Doppler velocities in fetuses with hypoplastic left heart syndrome. Ann Pediatr Cardiol. 2011 Jul;4(2):129-34. doi: 10.4103/0974-2069.84650. PMID: 21976871; PMCID: PMC3180969.
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Ann Pediatr Cardiol. 2011 Jul;4(2):129-34. doi: 10.4103/0974-2069.84650.

Myocardial tissue Doppler velocities in fetuses with hypoplastic left heart syndrome.

Annals of pediatric cardiology

Himesh V Vyas, Benjamin W Eidem, Frank Cetta, Ganesh Acharya, James Huhta, David Roberson, Bettina Cuneo

Affiliations

  1. Department of Pediatrics, Division of Pediatric Cardiology, Mayo Clinic College of Medicine, Rochester, MN, USA.

PMID: 21976871 PMCID: PMC3180969 DOI: 10.4103/0974-2069.84650

Abstract

BACKGROUND: Tissue Doppler Imaging (TDI) is a sensitive index of myocardial function. Its role in the fetus has not been extensively evaluated.

OBJECTIVE: To compare myocardial tissue Doppler velocities in fetuses with hypoplastic left heart syndrome (HLHS) to those of normal fetuses (matched for gestational age.)

METHODS: Cross-sectional retrospective study conducted at 2 large perinatal centers (2003-2007). Fetuses with HLHS (n = 13) were compared with normal fetuses (n = 207) in 5 gestational age groups. TDI data included peak systolic (s'), peak early (e'), and late diastolic velocities (a'). Linear regression was used to compare TDI parameters in fetuses with HLHS to normal fetuses matched for gestational age.

RESULTS: Fetuses with HLHS had significantly reduced lateral tricuspid annular e' as compared to normal fetuses. Both normal fetuses and those with HLHS had linear increase in TDI velocities with advancing gestational age.

CONCLUSIONS: TDI velocities are abnormal in fetuses with HLHS. TDI can be useful in serial follow-up of cardiac function in fetuses with HLHS.

Keywords: Cardiac function; fetal echocardiography; hypoplastic left heart syndrome; tissue doppler

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