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Wong KP, Lang BH. The role of prophylactic central neck dissection in differentiated thyroid carcinoma: issues and controversies. J Oncol. 2011;2011:127929doi: 10.1155/2011/127929.
Wong, K. P., & Lang, B. H. (2011). The role of prophylactic central neck dissection in differentiated thyroid carcinoma: issues and controversies. Journal of oncology, 2011127929. https://doi.org/10.1155/2011/127929
Wong, Kai-Pun, and Lang, Brian Hung-Hin. "The role of prophylactic central neck dissection in differentiated thyroid carcinoma: issues and controversies." Journal of oncology vol. 2011 (2011): 127929. doi: https://doi.org/10.1155/2011/127929
Wong KP, Lang BH. The role of prophylactic central neck dissection in differentiated thyroid carcinoma: issues and controversies. J Oncol. 2011;2011:127929. doi: 10.1155/2011/127929. Epub 2011 Sep 29. PMID: 21977029; PMCID: PMC3184411.
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J Oncol. 2011;2011:127929. doi: 10.1155/2011/127929. Epub 2011 Sep 29.

The role of prophylactic central neck dissection in differentiated thyroid carcinoma: issues and controversies.

Journal of oncology

Kai-Pun Wong, Brian Hung-Hin Lang

Affiliations

  1. Division of Endocrine Surgery, Department of Surgery, Queen Mary Hospital, The University of Hong Kong, Pokfulam Road, Hong Kong.

PMID: 21977029 PMCID: PMC3184411 DOI: 10.1155/2011/127929

Abstract

Prophylactic central neck dissection (pCND) in differentiated thyroid carcinoma (DTC) is one of the most controversial surgical subjects in recent times. To date, there is little evidence to support the practice of pCND in patients with DTC undergoing total thyroidectomy. Although the recently revised American Thyroid Association (ATA) guideline has clarified many inconsistencies regarding pCND and has recommended pCND in "high-risk" patients, many issues and controversies surrounding the subject of pCND in DTC remain. The recent literature has revealed an insignificant trend toward lower recurrence rate in patients with DTC who undergo total thyroidectomy and pCND than those who undergo total thyroidectomy alone. However, this was subjected to biases, and there are concerns whether pCND should be performed by all surgeons who manage DTC because of increased surgical morbodity. Performing a unilateral pCND may be better than a bilateral pCND given its lower surgical morbidity. Further studies in this controversial subject are much needed.

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