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Zhang J, Cohn C, Qiu W, et al. Atomic force microscopy of electrospun organic-inorganic lipid nanofibers. Appl Phys Lett. 2011;99(10):103702-1037023doi: 10.1063/1.3635783.
Zhang, J., Cohn, C., Qiu, W., Zha, Z., Dai, Z., & Wu, X. (2011). Atomic force microscopy of electrospun organic-inorganic lipid nanofibers. Applied physics letters, 99(10), 103702-1037023. https://doi.org/10.1063/1.3635783
Zhang, Jinhong, et al. "Atomic force microscopy of electrospun organic-inorganic lipid nanofibers." Applied physics letters vol. 99,10 (2011): 103702-1037023. doi: https://doi.org/10.1063/1.3635783
Zhang J, Cohn C, Qiu W, Zha Z, Dai Z, Wu X. Atomic force microscopy of electrospun organic-inorganic lipid nanofibers. Appl Phys Lett. 2011 Sep 05;99(10):103702-1037023. doi: 10.1063/1.3635783. Epub 2011 Sep 08. PMID: 21990942; PMCID: PMC3189251.
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Appl Phys Lett. 2011 Sep 05;99(10):103702-1037023. doi: 10.1063/1.3635783. Epub 2011 Sep 08.

Atomic force microscopy of electrospun organic-inorganic lipid nanofibers.

Applied physics letters

Jinhong Zhang, Celine Cohn, Weiguo Qiu, Zhengbao Zha, Zhifei Dai, Xiaoyi Wu

PMID: 21990942 PMCID: PMC3189251 DOI: 10.1063/1.3635783

Abstract

An organic-inorganic hybridization strategy has been proposed to synthesize polymerizable lipid-based materials for the creation of highly stable lipid-mimetic nanostructures. We employ atomic force microscopy (AFM) to analyze the surface morphology and mechanical property of electrospun cholesteryl-succinyl silane (CSS) nanofibers. The AFM nanoindentation of the CSS nanofibers reveals elastic moduli of 55.3 ± 27.6 to 70.8 ± 35 MPa, which is significantly higher than the moduli of natural phospholipids and cholesterols. The study shows that organic-inorganic hybridization is useful in the design of highly stable lipid-based materials.

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