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Taddio A, Cimaz R, Caputo R, et al. Childhood chronic anterior uveitis associated with vernal keratoconjunctivitis (VKC): successful treatment with topical tacrolimus. Case series. Pediatr Rheumatol Online J. 2011;9(1):34doi: 10.1186/1546-0096-9-34.
Taddio, A., Cimaz, R., Caputo, R., de Libero, C., Di Grande, L., Simonini, G., Mori, F., Novembre, E., & Pucci, N. (2011). Childhood chronic anterior uveitis associated with vernal keratoconjunctivitis (VKC): successful treatment with topical tacrolimus. Case series. Pediatric rheumatology online journal, 9(1), 34. https://doi.org/10.1186/1546-0096-9-34
Taddio, Andrea, et al. "Childhood chronic anterior uveitis associated with vernal keratoconjunctivitis (VKC): successful treatment with topical tacrolimus. Case series." Pediatric rheumatology online journal vol. 9,1 (2011): 34. doi: https://doi.org/10.1186/1546-0096-9-34
Taddio A, Cimaz R, Caputo R, de Libero C, Di Grande L, Simonini G, Mori F, Novembre E, Pucci N. Childhood chronic anterior uveitis associated with vernal keratoconjunctivitis (VKC): successful treatment with topical tacrolimus. Case series. Pediatr Rheumatol Online J. 2011 Nov 02;9(1):34. doi: 10.1186/1546-0096-9-34. PMID: 22047067; PMCID: PMC3221618.
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Pediatr Rheumatol Online J. 2011 Nov 02;9(1):34. doi: 10.1186/1546-0096-9-34.

Childhood chronic anterior uveitis associated with vernal keratoconjunctivitis (VKC): successful treatment with topical tacrolimus. Case series.

Pediatric rheumatology online journal

Andrea Taddio, Rolando Cimaz, Roberto Caputo, Cinzia de Libero, Laura Di Grande, Gabriele Simonini, Francesca Mori, Elio Novembre, Neri Pucci

Affiliations

  1. Institute for Maternal and Child Health - IRCCS "Burlo Garofolo" - Trieste and University of Trieste, Via dell'Istria 65/1, 34100, Trieste, Italy. [email protected].

PMID: 22047067 PMCID: PMC3221618 DOI: 10.1186/1546-0096-9-34

Abstract

Uveitis treatment involves topical corticosteroids along with cycloplegic-mydriatics. Particularly severe cases may require systemic corticosteroids and immunosuppressive drugs. Vernal keratoconjunctivitis (VKC) treatment consists of a brief period of topical corticosteroids and/or cyclosporine. In patients refractory to traditional treatment, the use of 0.1% topical ophtalmic FK- 506 (tacrolimus) ointment has been occasionally reported.This is the first report of the coexistence of uveitis and VKC. The documented response to topical tacrolimus eyedrop of uveitis and VKC is also of interest, in particular since to our knowledge there are no published reports on its clinical use in uveitis.

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