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Shahrun Niza AS, Rohaizak M, Naqiyah I, et al. Isolated ipsilateral nipple recurrence: important lessons to learn. Malays J Med Sci. 2011;18(2):82-4
Shahrun Niza, A. S., Rohaizak, M., Naqiyah, I., Srijit, D., & Noraidah, M. (2011). Isolated ipsilateral nipple recurrence: important lessons to learn. The Malaysian journal of medical sciences : MJMS, 18(2), 82-4.
Shahrun Niza, Abdullah Suhami, et al. "Isolated ipsilateral nipple recurrence: important lessons to learn." The Malaysian journal of medical sciences : MJMS vol. 18,2 (2011): 82-4.
Shahrun Niza AS, Rohaizak M, Naqiyah I, Srijit D, Noraidah M. Isolated ipsilateral nipple recurrence: important lessons to learn. Malays J Med Sci. 2011 Apr;18(2):82-4. PMID: 22135593; PMCID: PMC3216209.
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Malays J Med Sci. 2011 Apr;18(2):82-4.

Isolated ipsilateral nipple recurrence: important lessons to learn.

The Malaysian journal of medical sciences : MJMS

Abdullah Suhami Shahrun Niza, Muhammad Rohaizak, Ibrahim Naqiyah, Das Srijit, Masir Noraidah

Affiliations

  1. Department of Surgery, Universiti Kebangsaan Malaysia Medical Centre, Jalan Yaakub Latiff, Bandar Tun Razak, 56000 Kuala Lumpur, Malaysia.

PMID: 22135593 PMCID: PMC3216209

Abstract

Most breast cancer recurrences occur in the surgical scars or within other quadrants of the same breast. Isolated tumour recurrence occurring in the nipple after breast-conserving surgery and radiotherapy is extremely unusual. The reason for this is unknown, but is speculated to be due to involved surgical margins or an occult involvement of the nipple-areolar complex in a breast cancer of the same breast. We present a case of a 44-year-old Indian woman who had recurrent tumour over her right nipple after an ipsilateral breast-conserving surgery that was followed by adjuvant chemotherapy and radiotherapy. There was no typical malignancy features from the mammogram. However, histopathological study confirmed a malignant growth that infiltrated into the dermis and the underneath breast tissue. Completion mastectomy was then performed and the patient was later treated with Taxane-based chemotherapy. Nipple recurrence after breast-conserving surgery and adjuvant radiotherapy may be confused with other nipple conditions such as Paget's disease of the breast. Comprehensive assessments, which include mammogram and biopsy, have proved that such recurrence do occur, as presented in this case. This warrants a specific management strategy.

Keywords: breast-conserving surgery; diagnosis; nipple; recurrence; surgical oncology

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