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Chemistry. 2011 Dec 09;17(50):14164-9. doi: 10.1002/chem.201102182. Epub 2011 Nov 23.

Highly selective electrosynthesis of biphenols on graphite electrodes in fluorinated media.

Chemistry (Weinheim an der Bergstrasse, Germany)

Axel Kirste, Shotaro Hayashi, Gregor Schnakenburg, Itamar M Malkowsky, Florian Stecker, Andreas Fischer, Toshio Fuchigami, Siegfried R Waldvogel

Affiliations

  1. Rheinische Friedrich-Wilhelms-Universität Bonn, Kekulé-Institut für Organische Chemie und Biochemie, Gerhard-Domagk-Strasse 1, 53121 Bonn, Germany.

PMID: 22109730 DOI: 10.1002/chem.201102182

Abstract

The direct and selective phenol coupling reaction that provides biphenols still represents a challenge in organic synthesis. The recently developed electrosynthesis on boron-doped diamond anodes with fluorinated additives was developed further to allow the application to less-expensive electrodes and fluorinated media. This advanced protocol allows the highly selective anodic phenol coupling reaction on graphite with a broad scope.

Copyright © 2011 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

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