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Bradley R, O'Toole DT, Wells DE, et al. Clinical biochemistry and pathology of mature beef cattle following ante-mortem intravenous administration of a commercial papain preparation. Meat Sci. 1987;19(1):39-51doi: 10.1016/0309-1740(87)90098-2.
Bradley, R., O'Toole, D. T., Wells, D. E., Anderson, P. H., Hartley, P., Berrett, S., Morris, J. E., Insch, C. G., & Hayward, E. A. (1987). Clinical biochemistry and pathology of mature beef cattle following ante-mortem intravenous administration of a commercial papain preparation. Meat science, 19(1), 39-51. https://doi.org/10.1016/0309-1740(87)90098-2
Bradley, R, et al. "Clinical biochemistry and pathology of mature beef cattle following ante-mortem intravenous administration of a commercial papain preparation." Meat science vol. 19,1 (1987): 39-51. doi: https://doi.org/10.1016/0309-1740(87)90098-2
Bradley R, O'Toole DT, Wells DE, Anderson PH, Hartley P, Berrett S, Morris JE, Insch CG, Hayward EA. Clinical biochemistry and pathology of mature beef cattle following ante-mortem intravenous administration of a commercial papain preparation. Meat Sci. 1987;19(1):39-51. doi: 10.1016/0309-1740(87)90098-2. PMID: 22055787.
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Meat Sci. 1987;19(1):39-51. doi: 10.1016/0309-1740(87)90098-2.

Clinical biochemistry and pathology of mature beef cattle following ante-mortem intravenous administration of a commercial papain preparation.

Meat science

R Bradley, D T O'Toole, D E Wells, P H Anderson, P Hartley, S Berrett, J E Morris, C G Insch, E A Hayward

Affiliations

  1. Pathology Department, Central Veterinary Laboratory, New Haw, Weybridge, KT15 3NB, Great Britain.

PMID: 22055787 DOI: 10.1016/0309-1740(87)90098-2

Abstract

Ten healthy beef cattle in a commercial abbatoir were treated intravenously before slaughter with a commercial papain-based tenderising injection (Pro Ten). Animals were observed for behavioural and clinical abnormalities following treatment. Serum enzyme activities were measured pre-treatment and post-treatment immediately pre-slaughter < 6 min later to detect liver and muscle damage. Carcases were examined grossly post mortem. Histological examination of liver, kidney and muscle followed. Nine contemporary, age-matched controls were similarly examined. It was concluded that ProTen treatment did not cause any detectable hepatocellular or renal damage and there was no significant difference in the parameters examined between treated and untreated cattle. A decision to ban the use of ProTen in cattle could not therefore be based on the premise that it interfered with the animal's welfare in the period following injection under the conditions pertaining in this experiment.

Copyright © 1987. Published by Elsevier Ltd.

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