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Veerabahu BG, Chandrasekaran S, Alam MN, et al. Papillon-Lefévre syndrome. J Oral Maxillofac Pathol. 2011;15(3):352-7doi: 10.4103/0973-029X.86724.
Veerabahu, B. G., Chandrasekaran, S., Alam, M. N., & Krishnan, M. (2011). Papillon-Lefévre syndrome. Journal of oral and maxillofacial pathology : JOMFP, 15(3), 352-7. https://doi.org/10.4103/0973-029X.86724
Veerabahu, Bagavad Gita, et al. "Papillon-Lefévre syndrome." Journal of oral and maxillofacial pathology : JOMFP vol. 15,3 (2011): 352-7. doi: https://doi.org/10.4103/0973-029X.86724
Veerabahu BG, Chandrasekaran S, Alam MN, Krishnan M. Papillon-Lefévre syndrome. J Oral Maxillofac Pathol. 2011 Sep;15(3):352-7. doi: 10.4103/0973-029X.86724. PMID: 22144846; PMCID: PMC3227270.
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J Oral Maxillofac Pathol. 2011 Sep;15(3):352-7. doi: 10.4103/0973-029X.86724.

Papillon-Lefévre syndrome.

Journal of oral and maxillofacial pathology : JOMFP

Bagavad Gita Veerabahu, Sc Chandrasekaran, Mohammed Nazish Alam, Mahalakshmi Krishnan

Affiliations

  1. Department of Periodontology, Sree Balaji Dental College and Hospital, Chennai, India.

PMID: 22144846 PMCID: PMC3227270 DOI: 10.4103/0973-029X.86724

Abstract

The goal of periodontal therapy has always been regeneration of the lost tissues. However, conventional periodontal therapy has not always been successful in achieving regeneration, especially when it is part of a syndrome. This case report involves a 13-year old male patient with the chief complaint of mobile teeth for over 3 months. His dental history revealed early loss of primary dentition, around 3-4 years of age and that he noticed mobility of permanent incisors and molars at 9-10 years. Keratotic skin lesions on the palms and soles were present since the age of 3 years. Full mouth intra-oral periapical radiographs showed extensive bone loss upto apical thirds of the teeth and an orthopantamograph showed "floating in air" appearance. Further, a lateral cephalogram was taken to rule out any calcifications of the duramater. The case was provisionally diagnosed to be Papillon Lefévre syndrome. A conventional polymerase chain reaction assay was also done to assess the virulence genes in aggressive periodontitis. Though the management of PLS involves the regular phases of periodontal therapy, namely, etiotropic, surgical, restorative and maintenance phases, the complete esthetic and functional rehabilitation also involves other specialities especially prosthodontic and dermatologic and later an implantologist. After appropriate periodontal and prosthodontic management, the patient has been followed up for over a year and is maintaining in a stable condition.

Keywords: Generalized aggressive periodontitis; Palmoplantar hyperkeratosis; Papillon-Lefévre syndrome; neutrophil function tests; polymerase chain reaction

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