Display options
Share it on

Indian J Nephrol. 2012 Jan;22(1):13-7. doi: 10.4103/0971-4065.91181.

The incidence of renal artery stenosis in the patients referred for coronary artery bypass grafting.

Indian journal of nephrology

F Liang, D Y Hu, M Y Wu, T C Li, C Z Tang, J Y Wang, C L Lu

Affiliations

  1. Department of Cardiology, Daxing Hospital, Capital University of Medical Science, Beijing, People's Republic of China.

PMID: 22279337 PMCID: PMC3263057 DOI: 10.4103/0971-4065.91181

Abstract

Multivessel coronary disease or peripheral arterial disease is the clinical clue to diagnosis of renal artery stenosis (RAS). RAS is considered equivalent to coronary artery disease in terms of cardiovascular risk. In this study, we evaluated the incidence of RAS in the patients who were proposed to undergo coronary artery bypass grafting (CABG). Diagnostic evaluations of coronary arteriography and renal artery angiography were performed during the same procedure; the patients who were proposed for CABG in terms of CAD anatomy and clinical manifestation were enrolled. RAS was evaluated and a diameter stenosis of ≥50% was considered as significant RAS; significant RAS patients were divided into five groups. The five groups of RAS were as follows: (1) unilateral RAS ≥50-70%, (2) unilateral RAS ≥70%, (3) bilateral RAS ≥50-70%, (4) one-renal-artery stenosis ≥50-70%, contralateral RAS ≥70%, and (5) bilateral renal artery stenosis ≥70%. A total of 151 patients were enrolled, and RAS (≥50% stenosis in either or both renal arteries) was identified in 47.02% (71/151) patients. Unilateral RAS ≥50-70% was identified in 16.6% (25/151) patients, unilateral RAS ≥70% in 4.6% (7/151) patients, bilateral RAS ≥50-70% in 7.9% (12/151) patients, one-renal-artery stenosis ≥50-70% and contralateral RAS ≥70% in 7.9% (12/151) patients, and bilateral RAS ≥70% was in 9.9%(15/151) patients. The incidence of RAS was 29.03% (18/62) in patients aged ≤60 years, 60% (36/60) in patients aged >60 and ≤70 years, and 58.62% (17/29) in patients aged >70 years. The incidence of RAS was significantly higher in patients aged >60 - ≤70, and >70 years than patients aged ≤60 years (P = 0.001 and P = 0.007, respectively). There was a trend that the incidence of RAS in patients with hypertension [HTN, 50.40% (64/127)] was higher than those without HTN (29.17%, 7/24), with P = 0.056. The incidence of RAS was 47.02% in patients who were proposed for CABG; bilateral RAS of ≥70% was 9.9%. Older age and HTN were associated with RAS in patients who were referred for CABG. This study indicates that the incidence of RAS was high in the patients referred for CABG, and the renal function should be taken care of.

Keywords: Coronary arteriography; coronary artery bypass grafting; coronary heart disease; renal artery stenosis

References

  1. Vasc Med. 2008;13(2):141-56 - PubMed
  2. J Am Soc Nephrol. 1992 May;2(11):1608-16 - PubMed
  3. Am J Cardiol. 2007 Jul 15;100(2):273-9 - PubMed
  4. Vasc Med. 2009 Aug;14(3):277-81 - PubMed
  5. Can J Cardiol. 2009 Jan;25(1):19-24 - PubMed
  6. Ann Intern Med. 2001 Oct 16;135(8 Pt 1):616-32 - PubMed
  7. Heart. 2002 Aug;88(2):193-7 - PubMed
  8. Clin J Am Soc Nephrol. 2006 Mar;1(2):172-81 - PubMed
  9. Cleve Clin J Med. 2010 Mar;77(3):178-89 - PubMed
  10. J Am Coll Cardiol. 2004 May 5;43(9):1606-13 - PubMed
  11. N Engl J Med. 2001 Feb 8;344(6):431-42 - PubMed
  12. Nephrol Dial Transplant. 2003 Jun;18(6):1147-51 - PubMed
  13. J Hypertens. 2007 Mar;25(3):663-70 - PubMed
  14. J Am Soc Nephrol. 2006 Jul;17(7):2069-74 - PubMed
  15. Am Heart J. 2005 Dec;150(6):1204-11 - PubMed
  16. Arch Iran Med. 2009 May;12(3):250-5 - PubMed
  17. Nephron Clin Pract. 2008;108(1):c56-66 - PubMed
  18. Am J Nephrol. 2007;27(2):212-20 - PubMed
  19. Kidney Int. 1998 Mar;53(3):735-42 - PubMed
  20. Kidney Int. 2001 Oct;60(4):1490-7 - PubMed

Publication Types