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Immunity. 2012 Jan 27;36(1):5-7. doi: 10.1016/j.immuni.2012.01.004.

The aryl hydrocarbon receptor: a sentinel safeguarding the survival of immune cells in the gut.

Immunity

Hergen Spits, Jenny Mjösberg

Affiliations

  1. Tytgat Institute of Intestinal and Liver Research at the Academic Medical Center, Amsterdam, The Netherlands. [email protected]

PMID: 22284414 DOI: 10.1016/j.immuni.2012.01.004

Abstract

Innate lymphoid cells (ILCs) regulate the epithelial barrier function and immunity in the gut. How ILC numbers are maintained is unknown. In this issue of Immunity, Qiu et al. (2012) report that the transcription factor aryl hydrocarbon receptor controls survival and function of gut-residing ILCs.

Copyright © 2012 Elsevier Inc. All rights reserved.

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