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Blood. 2012 Feb 02;119(5):1103-4. doi: 10.1182/blood-2011-12-394544.

TM hidden treasure: lectin-like domain.

Blood

Kenneth K Wu

Affiliations

  1. National Health Research Institutes.

PMID: 22308281 DOI: 10.1182/blood-2011-12-394544

Abstract

In this issue of Blood, Kuo et al have used recombinant lectin-like domain of thrombomodulin domain 1 (TMD1) to demonstrate the action of lectin-like domain in blocking Lewis Y antigen (LeY)–mediated angiogenesis and control of tumor growth.

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