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Bajwa SJ, Kwatra IS. Reno-endocrinal disorders: A basic understanding of the molecular genetics. Indian J Endocrinol Metab. 2012;16(2):158-63doi: 10.4103/2230-8210.93731.
Bajwa, S. J., & Kwatra, I. S. (2012). Reno-endocrinal disorders: A basic understanding of the molecular genetics. Indian journal of endocrinology and metabolism, 16(2), 158-63. https://doi.org/10.4103/2230-8210.93731
Bajwa, Sukhminder Jit Singh, and Kwatra, Ishwardip Singh. "Reno-endocrinal disorders: A basic understanding of the molecular genetics." Indian journal of endocrinology and metabolism vol. 16,2 (2012): 158-63. doi: https://doi.org/10.4103/2230-8210.93731
Bajwa SJ, Kwatra IS. Reno-endocrinal disorders: A basic understanding of the molecular genetics. Indian J Endocrinol Metab. 2012 Mar;16(2):158-63. doi: 10.4103/2230-8210.93731. PMID: 22470850; PMCID: PMC3313731.
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Indian J Endocrinol Metab. 2012 Mar;16(2):158-63. doi: 10.4103/2230-8210.93731.

Reno-endocrinal disorders: A basic understanding of the molecular genetics.

Indian journal of endocrinology and metabolism

Sukhminder Jit Singh Bajwa, Ishwardip Singh Kwatra

Affiliations

  1. Department of Anaesthesiology and Intensive Care, Gian Sagar Medical College and Hospital, Ram Nagar, Banur, Punjab, India.

PMID: 22470850 PMCID: PMC3313731 DOI: 10.4103/2230-8210.93731

Abstract

The successful management of endocrine diseases is greatly helped by the complete understanding of the underlying pathology. The knowledge about the molecular genetics contributes immensely in the appropriate identification of the causative factors of the diseases and their subsequent management. The fields of nephrology and endocrinology are also interrelated to a large extent. Besides performing the secretory functions, the renal tissue also acts as target organ for many hormones such as antidiuretic hormone (ADH), atrial natriuretic peptides (ANP), and aldosterone. Understanding the molecular genetics of these hormones is important because the therapeutic interventions in many of these conditions is related to shared renal and endocrine functions, including the anemia of renal disease, chronic kidney disease, mineral bone disorders, and hypertension related to chronic kidney disease. Their understanding and in-depth knowledge is very essential in designing and formulating the therapeutic plans and innovating new management strategies. However, we still have to go a long way in order to completely understand the various confounding causative relationships between the pathology and disease of these reno-endocrinal manifestations.

Keywords: Erythropoietin; molecular genetics; parathyroid hormone; renin; vitamin D

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