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Kotsia AP, Dimitriadis G, Baltogiannis GG, et al. Torsade de Pointes and Persistent QTc Prolongation after Intravenous Amiodarone. Case Rep Med. 2012;2012:673019doi: 10.1155/2012/673019.
Kotsia, A. P., Dimitriadis, G., Baltogiannis, G. G., & Kolettis, T. M. (2012). Torsade de Pointes and Persistent QTc Prolongation after Intravenous Amiodarone. Case reports in medicine, 2012673019. https://doi.org/10.1155/2012/673019
Kotsia, Anna P, et al. "Torsade de Pointes and Persistent QTc Prolongation after Intravenous Amiodarone." Case reports in medicine vol. 2012 (2012): 673019. doi: https://doi.org/10.1155/2012/673019
Kotsia AP, Dimitriadis G, Baltogiannis GG, Kolettis TM. Torsade de Pointes and Persistent QTc Prolongation after Intravenous Amiodarone. Case Rep Med. 2012;2012:673019. doi: 10.1155/2012/673019. Epub 2012 Mar 05. PMID: 22474460; PMCID: PMC3303706.
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Case Rep Med. 2012;2012:673019. doi: 10.1155/2012/673019. Epub 2012 Mar 05.

Torsade de Pointes and Persistent QTc Prolongation after Intravenous Amiodarone.

Case reports in medicine

Anna P Kotsia, Georgios Dimitriadis, Giannis G Baltogiannis, Theofilos M Kolettis

Affiliations

  1. Department of Cardiology, University Hospital of Ioannina, 1 Stavrou Niarxou Avenue, 45110 Ioannina, Greece.

PMID: 22474460 PMCID: PMC3303706 DOI: 10.1155/2012/673019

Abstract

We report a case of torsade de pointes after intravenous amiodarone and concurrent hypokalemia. Despite treatment cessation and correction of electrolyte abnormalities, excessive QTc prolongation was noted, which persisted for 14 days. This prolonged course for QTc normalization may be attributed to the high rate of amiodarone loading and concurrent electrolyte disturbances coupled with possible underlying individual variability in pharmacokinetics.

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