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Kaya B, Aras O, Bat O, et al. Steroid-induced sigmoid diverticular perforation in a patient with temporal arteritis: a rare clinical pathology. Clin Med Insights Pathol. 2012;5:11-4doi: 10.4137/CPath.S7924.
Kaya, B., Aras, O., Bat, O., Bulut, N. E., & Memisoglu, K. (2012). Steroid-induced sigmoid diverticular perforation in a patient with temporal arteritis: a rare clinical pathology. Clinical medicine insights. Pathology, 511-4. https://doi.org/10.4137/CPath.S7924
Kaya, Bulent, et al. "Steroid-induced sigmoid diverticular perforation in a patient with temporal arteritis: a rare clinical pathology." Clinical medicine insights. Pathology vol. 5 (2012): 11-4. doi: https://doi.org/10.4137/CPath.S7924
Kaya B, Aras O, Bat O, Bulut NE, Memisoglu K. Steroid-induced sigmoid diverticular perforation in a patient with temporal arteritis: a rare clinical pathology. Clin Med Insights Pathol. 2012;5:11-4. doi: 10.4137/CPath.S7924. Epub 2012 Mar 29. PMID: 22493565; PMCID: PMC3320117.
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Clin Med Insights Pathol. 2012;5:11-4. doi: 10.4137/CPath.S7924. Epub 2012 Mar 29.

Steroid-induced sigmoid diverticular perforation in a patient with temporal arteritis: a rare clinical pathology.

Clinical medicine insights. Pathology

Bulent Kaya, Orhan Aras, Orhan Bat, Nuriye Esen Bulut, Kemal Memisoglu

Affiliations

  1. Fatih Sultan Mehmet Training and Research Hospital, Department of General Surgery, Istanbul, Turkey.

PMID: 22493565 PMCID: PMC3320117 DOI: 10.4137/CPath.S7924

Abstract

Corticosteroids are used in the treatment of many rheumatological diseases including temporal arteritis. The gastrointestinal perforation during corticosteroid treatment is a serious complication. Colon perforation after steroid use was first reported by Beck et al in 1950.1 Although the pathophysiological mechanism is not understood clearly, it is claimed that steroids probably by disturbing the intestinal mucosal barrier, facilitate the intestinal perforation. The long term treatment with corticosteroids increases the risk of colon perforation. We are presenting a patient who was taking corticosteroid due to temporal arteritis for two years and operated with sigmoid diverticular perforation.

Keywords: perforation; sigmoid diverticulitis; steroid treatment

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