Display options
Share it on

Obstet Gynecol Int. 2012;2012:195954. doi: 10.1155/2012/195954. Epub 2012 Feb 07.

Opioid dependent and pregnant: what are the best options for mothers and neonates?.

Obstetrics and gynecology international

Annemarie Unger, Verena Metz, Gabriele Fischer

Affiliations

  1. Department of Psychiatry and Psychotherapy, University Hospital of Vienna, 1090 Vienna, Austria.

PMID: 22496696 PMCID: PMC3306958 DOI: 10.1155/2012/195954

Abstract

Pregnancy in opioid-dependent women is a major public health issue. Women who are afflicted by opioid addiction are a highly vulnerable group of patients frequently becoming pregnant unplanned and at risk of adverse pregnancy outcomes and peri-natal complications. Opioid agonist maintenance treatment is the best option for the majority of women. Ideally, early and closely monitored treatment in an interdisciplinary team approach including social workers, nurses, psychologists, psychiatrists, gynecologists, anesthesiologists, and pediatricians should be provided. The treatment of comorbid psychiatric conditions, the resolution of financial, legal, and housing issues, and the psychosocial support provided have a significant effect on optimizing pregnancy outcomes. This paper aims to update health professionals in the field of gynecology and obstetrics on the latest optimal treatment approaches for mothers suffering from opioid dependence and their neonates.

References

  1. Eur Neuropsychopharmacol. 1999 Mar;9(3):227-33 - PubMed
  2. Addict Dis. 1975;2(1-2):141-58 - PubMed
  3. Anaesthesia. 2006 Mar;61(3):269-76 - PubMed
  4. Int J Clin Pharmacol Biopharm. 1975 Jul;12(1-2):19-32 - PubMed
  5. Pediatrics. 2008 Jan;121(1):106-14 - PubMed
  6. Int J Pediatr. 2011;2011:935631 - PubMed
  7. Addiction. 2006 Feb;101(2):275-81 - PubMed
  8. Clin Perinatol. 1999 Mar;26(1):173-83 - PubMed
  9. J Addict Med. 2012 Mar;6(1):18-23 - PubMed
  10. Drug Alcohol Depend. 2004 Sep 6;75(3):253-60 - PubMed
  11. Pediatrics. 2001 Sep;108(3):776-89 - PubMed
  12. Drug Alcohol Depend. 2010 Jun 1;109(1-3):198-204 - PubMed
  13. J Addict Med. 2008 Sep;2(3):113-20 - PubMed
  14. Am J Epidemiol. 2002 Feb 15;155(4):293-301 - PubMed
  15. Addiction. 2008 Sep;103(9):1429-40 - PubMed
  16. J Hum Lact. 2009 May;25(2):199-205 - PubMed
  17. N Engl J Med. 1990 Apr 26;322(17):1202-6 - PubMed
  18. Anesth Analg. 2009 Jan;108(1):308-15 - PubMed
  19. Addiction. 2010 Dec;105(12):2071-84 - PubMed
  20. Eur J Pain. 2012 Apr;16(4):574-84 - PubMed
  21. Reg Anesth Pain Med. 2004 Nov-Dec;29(6):576-91 - PubMed
  22. Cochrane Database Syst Rev. 2010 Oct 06;(10):CD002059 - PubMed
  23. Am J Addict. 2008 Sep-Oct;17(5):372-86 - PubMed
  24. Ann Pharmacother. 2004 Jun;38(6):949-53 - PubMed
  25. J Obstet Gynecol Neonatal Nurs. 2010 Sep-Oct;39(5):503-9 - PubMed
  26. Acta Obstet Gynecol Scand. 2007;86(2):185-90 - PubMed
  27. J Pharmacol Exp Ther. 1985 Apr;233(1):1-6 - PubMed
  28. Am J Perinatol. 2006 Oct;23(7):423-30 - PubMed
  29. Pediatrics. 2008 Apr;121(4):869; author reply 869-70 - PubMed
  30. J Addict Med. 2011 Dec;5(4):293-9 - PubMed
  31. Health Psychol. 2000 Nov;19(6):535-43 - PubMed
  32. Am J Obstet Gynecol. 2003 Aug;189(2):312-7 - PubMed
  33. Drug Alcohol Depend. 2006 May 20;82(3):250-7 - PubMed
  34. Ther Drug Monit. 2005 Aug;27(4):526-30 - PubMed
  35. Alcohol Clin Exp Res. 2005 May;29(5):801-9 - PubMed
  36. J Addict Dis. 2010 Apr;29(2):217-30 - PubMed
  37. Am J Addict. 2009 Mar-Apr;18(2):148-56 - PubMed
  38. Am J Orthopsychiatry. 2011 Apr;81(2):218-27 - PubMed
  39. Eur Addict Res. 2009;15(3):150-6 - PubMed
  40. Arch Womens Ment Health. 2006 Sep;9(5):279-84 - PubMed
  41. Drug Alcohol Depend. 2007 Mar 16;87(2-3):131-8 - PubMed
  42. Drug Alcohol Depend. 2005 Jul;79(1):1-10 - PubMed
  43. Biochem Pharmacol. 2005 Jun 15;69(12):1869-78 - PubMed
  44. Eur J Public Health. 2002 Sep;12(3):228-34 - PubMed
  45. Addiction. 2003 Jan;98(1):103-10 - PubMed
  46. Am J Drug Alcohol Abuse. 2009;35(3):151-6 - PubMed
  47. N Engl J Med. 2010 Dec 9;363(24):2320-31 - PubMed
  48. Addiction. 2000 Feb;95(2):239-44 - PubMed
  49. Am J Obstet Gynecol. 2002 Nov;187(5):1184-8 - PubMed
  50. Expert Opin Pharmacother. 2004 Mar;5(3):571-80 - PubMed
  51. Eur Addict Res. 2009;15(3):128-34 - PubMed
  52. J Subst Abuse Treat. 2011 Mar;40(2):199-202 - PubMed
  53. BJOG. 2009 Apr;116(5):665-71 - PubMed
  54. Drug Alcohol Depend. 2010 Nov 1;112(1-2):156-9 - PubMed
  55. J Pharmacol Exp Ther. 1999 Jan;288(1):260-9 - PubMed
  56. Drug Alcohol Depend. 2008 Jul 1;96(1-2):69-78 - PubMed
  57. Am J Epidemiol. 2002 Nov 1;156(9):797-802 - PubMed
  58. J Subst Abuse Treat. 2007 Jan;32(1):19-25 - PubMed
  59. Obstet Gynecol. 1998 Nov;92(5):854-8 - PubMed
  60. Addiction. 2011 Jul;106(7):1355-62 - PubMed
  61. Psychol Med. 2006 Dec;36(12):1663-70 - PubMed
  62. Pediatrics. 2006 Jun;117(6):e1163-9 - PubMed

Publication Types