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Albanese G, Kondo KL. Pharmacology of sclerotherapy. Semin Intervent Radiol. 2010;27(4):391-9doi: 10.1055/s-0030-1267848.
Albanese, G., & Kondo, K. L. (2010). Pharmacology of sclerotherapy. Seminars in interventional radiology, 27(4), 391-9. https://doi.org/10.1055/s-0030-1267848
Albanese, Giustino, and Kondo, Kimi L. "Pharmacology of sclerotherapy." Seminars in interventional radiology vol. 27,4 (2010): 391-9. doi: https://doi.org/10.1055/s-0030-1267848
Albanese G, Kondo KL. Pharmacology of sclerotherapy. Semin Intervent Radiol. 2010 Dec;27(4):391-9. doi: 10.1055/s-0030-1267848. PMID: 22550381; PMCID: PMC3324200.
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Semin Intervent Radiol. 2010 Dec;27(4):391-9. doi: 10.1055/s-0030-1267848.

Pharmacology of sclerotherapy.

Seminars in interventional radiology

Giustino Albanese, Kimi L Kondo

Affiliations

  1. Department of Radiology, University of Colorado Denver School of Medicine, Aurora, Colorado.

PMID: 22550381 PMCID: PMC3324200 DOI: 10.1055/s-0030-1267848

Abstract

Sclerotherapy is the therapeutic use of sclerosants in the controlled destruction of undesired target tissues. Sclerosants have been used in vascular and nonvascular settings, both as primary and adjunctive therapy. Effective sclerotherapy requires a conceptual understanding of key questions about the process being treated, including the method of delivery, the presence of flow, and the required contact time to initiate sclerosis. However, beyond technique and delivery, practical and safe application of sclerotherapy requires an understanding of the uses, limitations, dosing, and side effects of sclerosants used during interventional radiology procedures. Agents discussed here include detergents and surfactants [ethanol, Sotradecol(®) (Bioniche Pharma, Pointe Claire, Quebec and Angiodynamics, Latham, NY), ethanolamine oleate], hypertonics (saline, glucose), and a review of several other types that are used less frequently.

Keywords: Sclerotherapy; Sotradecol®; ethanol; ethanolamine oleate; hypertonic solutions; sclerosants

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