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Mathur NB, Joshi N, Singh T, et al. Congenital acute megakaryocytic leukemia. Indian J Med Paediatr Oncol. 2011;32(3):165-7doi: 10.4103/0971-5851.92821.
Mathur, N. B., Joshi, N., Singh, T., & Singh, M. (2011). Congenital acute megakaryocytic leukemia. Indian journal of medical and paediatric oncology : official journal of Indian Society of Medical & Paediatric Oncology, 32(3), 165-7. https://doi.org/10.4103/0971-5851.92821
Mathur, N B, et al. "Congenital acute megakaryocytic leukemia." Indian journal of medical and paediatric oncology : official journal of Indian Society of Medical & Paediatric Oncology vol. 32,3 (2011): 165-7. doi: https://doi.org/10.4103/0971-5851.92821
Mathur NB, Joshi N, Singh T, Singh M. Congenital acute megakaryocytic leukemia. Indian J Med Paediatr Oncol. 2011 Jul;32(3):165-7. doi: 10.4103/0971-5851.92821. PMID: 22557786; PMCID: PMC3342726.
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Indian J Med Paediatr Oncol. 2011 Jul;32(3):165-7. doi: 10.4103/0971-5851.92821.

Congenital acute megakaryocytic leukemia.

Indian journal of medical and paediatric oncology : official journal of Indian Society of Medical & Paediatric Oncology

N B Mathur, Neha Joshi, T Singh, Meeta Singh

Affiliations

  1. Department of Pediatrics, Maulana Azad Medical College, Delhi, India.

PMID: 22557786 PMCID: PMC3342726 DOI: 10.4103/0971-5851.92821

Abstract

Congenital leukemia (CL) is an extremely rare disorder in the newborn, significant proportion of which is of myeloid origin, primarily of M4 or M5 morphology. As compared to pediatric leukemia, CL is a more aggressive disease. Acute myeloid leukemia (AML-M7) or acute megakaryocytic leukemia is a rare type of AML with an incidence of 0.5 per million per year. Median age of presentation is 6 years, and children may present with a broad variety of symptoms including low-grade fever, diarrhea, easy bruising, failure to gain weight and life-threatening conditions.

Keywords: Congenital megakaryocytic leukemia; neonate; sepsis

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