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Anemia. 2012;2012:795439. doi: 10.1155/2012/795439. Epub 2012 Feb 28.

Prevalence of anemia and risk of adverse bleeding effect of drugs: implication for therapy.

Anemia

Ezekiel Uba Nwose

Affiliations

  1. Institute of Clinical Pathology & Medical Research, Nepean Hospital Pathology, Kingswood NSW 2747, Australia.

PMID: 22506109 PMCID: PMC3299257 DOI: 10.1155/2012/795439

Abstract

This study aimed to evaluate the progress in reduction of prevalence of anemia in rural Australia. It also investigates the prevalence of hypoviscosity in anaemia with a view to determine the fraction of anaemic patients at risk of drug-inducible exacerbation of anemia. Archived clinical pathology data (N = 130, 354) for the period of 1999 to 2008 were utilized. The prevalence of anemia and hypoviscosity was evaluated by working out (i) the number that fell within anemia definition as a percentage of the population and (ii) the number that fell within hypoviscosity definition as a percentage of anemic patients. The prevalence in anemic diabetes and dyslipidaemia was further determined. There was progressive reduction in anemia from 6.1% to 3.2% over the ten years period. Prevalence of anemia is statistically significantly higher in males than in females (P < 0.0001), but protein level is lower in anemic females than in anemic males (P < 0.01). The results further show that up to 75% of anemic patients may benefit from NSAID or salicylates. This paper highlights differences between genders. It suggests more concerted effort in men's health and speculates a new factor to investigate in women's health.

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