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Brazzelli V, Grasso V, Rivetti N, et al. Recurrence of mycosis fungoides on multiple melanocytic nevi: a case report and review of the literature. Case Rep Dermatol. 2012;4(1):92-7doi: 10.1159/000337750.
Brazzelli, V., Grasso, V., Rivetti, N., Fiandrino, G., Lucioni, M., & Borroni, G. (2012). Recurrence of mycosis fungoides on multiple melanocytic nevi: a case report and review of the literature. Case reports in dermatology, 4(1), 92-7. https://doi.org/10.1159/000337750
Brazzelli, Valeria, et al. "Recurrence of mycosis fungoides on multiple melanocytic nevi: a case report and review of the literature." Case reports in dermatology vol. 4,1 (2012): 92-7. doi: https://doi.org/10.1159/000337750
Brazzelli V, Grasso V, Rivetti N, Fiandrino G, Lucioni M, Borroni G. Recurrence of mycosis fungoides on multiple melanocytic nevi: a case report and review of the literature. Case Rep Dermatol. 2012 Jan;4(1):92-7. doi: 10.1159/000337750. Epub 2012 Apr 13. PMID: 22649337; PMCID: PMC3362184.
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Case Rep Dermatol. 2012 Jan;4(1):92-7. doi: 10.1159/000337750. Epub 2012 Apr 13.

Recurrence of mycosis fungoides on multiple melanocytic nevi: a case report and review of the literature.

Case reports in dermatology

Valeria Brazzelli, Vincenzo Grasso, Nicolò Rivetti, Giacomo Fiandrino, Marco Lucioni, Giovanni Borroni

Affiliations

  1. Department of Pediatric Sciences and Human and Hereditary Pathology, Institute of Dermatology, Pavia, Italy.

PMID: 22649337 PMCID: PMC3362184 DOI: 10.1159/000337750

Abstract

Melanocytic nevi represent a widespread cutaneous finding. Nevertheless, the presence of mycosis fungoides and melanocytic nevi in the same location is an extremely rare event. We report the case of a patient affected by mycosis fungoides and treated with PUVA therapy, with complete remission of the disease. Eight years after therapy discontinuation, he presented epidermal scaling and an erythematous perinevic halo on 3 old melanocytic lesions, the clinical aspect of which was highly suggestive for Meyerson nevi. The histological and immunohistochemical examination of an excised melanocytic lesion revealed histological features consistent with the diagnosis of mycosis fungoides superimposed on junctional melanocytic nevi. The finding of patches of mycosis fungoides superimposed on melanocytic nevi is a rare event; the confounding clinical appearance with eczematous changes around a pre-existing nevus may recall the halo dermatitis known as Meyerson phenomenon; this highlights the importance of clinical and histological examination to make the correct diagnosis of dermatological diseases.

Keywords: Halo phenomenon; Melanocytic nevi; Mycosis fungoides; PUVA therapy

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