Display options
Cite
Yi JW, Oh EM, Lee KE, et al. An exclusively dopamine secreting paraganglioma in the retroperitoneum: a first clinical case in Korea. J Korean Surg Soc. 2012;82(6):389-93doi: 10.4174/jkss.2012.82.6.389.
Yi, J. W., Oh, E. M., Lee, K. E., Choi, J. Y., Koo, d. o. . H., Kim, K. J., Jung, K. C., Kim, S. Y., & Youn, Y. K. (2012). An exclusively dopamine secreting paraganglioma in the retroperitoneum: a first clinical case in Korea. Journal of the Korean Surgical Society, 82(6), 389-93. https://doi.org/10.4174/jkss.2012.82.6.389
Yi, Jin Wook, et al. "An exclusively dopamine secreting paraganglioma in the retroperitoneum: a first clinical case in Korea." Journal of the Korean Surgical Society vol. 82,6 (2012): 389-93. doi: https://doi.org/10.4174/jkss.2012.82.6.389
Yi JW, Oh EM, Lee KE, Choi JY, Koo do H, Kim KJ, Jung KC, Kim SY, Youn YK. An exclusively dopamine secreting paraganglioma in the retroperitoneum: a first clinical case in Korea. J Korean Surg Soc. 2012 Jun;82(6):389-93. doi: 10.4174/jkss.2012.82.6.389. Epub 2012 May 29. PMID: 22708103; PMCID: PMC3373991.
Copy Download .nbib Format: NLM
Share it on

J Korean Surg Soc. 2012 Jun;82(6):389-93. doi: 10.4174/jkss.2012.82.6.389. Epub 2012 May 29.

An exclusively dopamine secreting paraganglioma in the retroperitoneum: a first clinical case in Korea.

Journal of the Korean Surgical Society

Jin Wook Yi, Eun Mee Oh, Kyu Eun Lee, June Young Choi, Do Hoon Koo, Kyung Joo Kim, Kyeong-Cheon Jung, Seong-Yeon Kim, Yeo-Kyu Youn

Affiliations

  1. Department of Surgery, Seoul National University Hospital, Seoul, Korea.

PMID: 22708103 PMCID: PMC3373991 DOI: 10.4174/jkss.2012.82.6.389

Abstract

Exclusively dopamine producing retroperitoneal paragangliomas are extremely rare. We have experienced the first Korean case managed successfully based on the proper evaluation. A 26-year-old female patient came to our attention after the accidental detection of an adrenal mass. She had no symptoms and denied any family history. Laboratory evaluations were normal but serum dopamine (425 ng/L) and 24-hour urine dopamine levels (1,565.3 µg/day) were elevated. She underwent laparoscopic right adrenalectomy. Histopathological diagnosis was a paraganglioma. After operation, dopamine levels in serum and 24-hour urine dropped to 0.09 ng/L and 388.4 µg/day. Dopamine producing paraganglioma elicit no clinical symptoms. Only the dopamine level is elevated in serum and 24-hour urine samples. Surgical resection without using preoperative alpha blockage is the treatment of choice. The prognosis for patients with this tumor tends to be poor because the diagnosis is usually delayed due to lack of symptoms.

Keywords: Adrenal glands; Adrenergic alpha-antagonists; Dopamine; Paraganglioma; Pheochromocytoma

References

  1. J Clin Endocrinol Metab. 2005 Apr;90(4):2068-75 - PubMed
  2. Singapore Med J. 2010 May;51(5):e89-93 - PubMed
  3. South Med J. 2003 Sep;96(9):914-7 - PubMed
  4. Am J Clin Pathol. 1979 Aug;72(2):175-85 - PubMed
  5. Surg Endosc. 2006 May;20(5):830-3 - PubMed
  6. Ann Clin Biochem. 2005 Jan;42(Pt 1):73-7 - PubMed
  7. World J Surg. 2005 Jul;29(7):909-13 - PubMed
  8. Am J Med. 1999 May;106(5):599-600 - PubMed
  9. J Endocrinol Invest. 1992 Oct;15(9):631-42 - PubMed
  10. Surgery. 1986 Dec;100(6):1154-62 - PubMed

Publication Types