Display options
Share it on

J Geriatr Oncol. 2012 Apr 01;3(2):90-97. doi: 10.1016/j.jgo.2012.01.002. Epub 2012 Jan 27.

Exercise and Cancer Treatment Symptoms in 408 Newly Diagnosed Older Cancer Patients.

Journal of geriatric oncology

Lisa K Sprod, Supriya G Mohile, Wendy Demark-Wahnefried, Michelle C Janelsins, Luke J Peppone, Gary R Morrow, Raymond Lord, Howard Gross, Karen M Mustian

Affiliations

  1. Department of Radiation Oncology, University of Rochester Medical Center, Rochester, New York.

PMID: 22712028 PMCID: PMC3376161 DOI: 10.1016/j.jgo.2012.01.002

Abstract

While the benefits of exercise for managing cancer-and treatment-related side effects has been shown among various populations of cancer survivors, a relative dearth of information exists among older cancer patients. OBJECTIVES: To determine the prevalence of exercise participation during and after primary cancer treatment in older (≥65 years) and the oldest (≥80 years) cancer patients and to examine the relationships between exercise, symptoms, and self-rated health (SRH). MATERIALS AND METHODS: 408 newly diagnosed older cancer patients (mean age=73, range=65-92) scheduled to receive chemotherapy and/or radiation therapy reported symptoms and SRH prior to, during, and 6 months after treatment, and exercise participation during and following treatment. RESULTS: Forty-six percent of older and 41% of the oldest patients reported exercising during treatment. Sixty percent of older and 68% of the oldest patients reported exercising in the 6 months thereafter. Older patients who exercised during treatment reported less shortness of breath and better SRH during treatment, and better SRH following treatment. The oldest patients who exercised during treatment reported less memory loss and better SRH during treatment and less fatigue and better SRH following treatment. The oldest patients who exercised following treatment reported less fatigue, skin problems, and total symptom burden following treatment. CONCLUSION: These data suggest a willingness of older cancer patients to attempt exercise during and after treatment. Exercise during these times is associated with less severe symptoms; further clinical research examining the efficacy of formal exercise interventions to reduce symptoms and improve SRH in older cancer patients is needed.

References

  1. J Clin Oncol. 2005 Jun 1;23(16):3830-42 - PubMed
  2. Cancer. 2000 Oct 1;89(7):1634-46 - PubMed
  3. Arch Phys Med Rehabil. 2006 Jul;87(7):885-96 - PubMed
  4. Cancer. 1999 May 15;85(10):2273-7 - PubMed
  5. J Oncol. 2009;2009:693458 - PubMed
  6. Crit Rev Oncol Hematol. 2004 Sep;51(3):249-61 - PubMed
  7. Support Care Cancer. 2008 Jan;16(1):3-8 - PubMed
  8. Arch Gerontol Geriatr. 2010 May-Jun;50(3):332-7 - PubMed
  9. Cancer Nurs. 2001 Feb;24(1):1-11 - PubMed
  10. J Clin Oncol. 2006 Jul 20;24(21):3465-73 - PubMed
  11. J Am Geriatr Soc. 2005 Jul;53(7):1168-78 - PubMed
  12. Cancer Causes Control. 2004 Dec;15(10):1035-56 - PubMed
  13. J Gerontol. 1990 Jan;45(1):M3-11 - PubMed
  14. Aging Clin Exp Res. 2008 Apr;20(2):159-70 - PubMed
  15. J Oncol Manag. 2005 Spring;14(2):47-50 - PubMed
  16. Cancer Nurs. 2006 May-Jun;29(3):214-24; quiz 225-6 - PubMed
  17. J Health Soc Behav. 1997 Mar;38(1):21-37 - PubMed
  18. J Clin Oncol. 2005 Feb 1;23(4):899-909 - PubMed
  19. Cancer Nurs. 2007 Sep-Oct;30(5):E35-45 - PubMed
  20. Cancer Nurs. 2007 Nov-Dec;30(6):421-33 - PubMed
  21. Cancer. 2004 Aug 15;101(4):851-7 - PubMed
  22. BMC Geriatr. 2011 Jan 27;11:5 - PubMed
  23. Med Sci Sports Exerc. 2009 Jul;41(7):1510-30 - PubMed
  24. Cancer. 2003 Apr 1;97(7):1746-57 - PubMed
  25. J Am Geriatr Soc. 2002 Dec;50(12):1921-8 - PubMed
  26. Support Care Cancer. 2011 Jul;19(7):1019-28 - PubMed
  27. Proc Natl Acad Sci U S A. 2005 Apr 12;102(15):5618-23 - PubMed
  28. Med Sci Sports Exerc. 2002 Dec;34(12):1863-7 - PubMed
  29. Psychooncology. 2002 Sep-Oct;11(5):389-400 - PubMed
  30. J Gerontol B Psychol Sci Soc Sci. 2011 Jul;66 Suppl 1:i82-90 - PubMed
  31. Aging Clin Exp Res. 2004 Jun;16(3):233-9 - PubMed
  32. Clin Nutr. 2007 Aug;26(4):389-99 - PubMed
  33. Nutr Cancer. 2002;42(2):143-57 - PubMed
  34. Semin Oncol. 2008 Dec;35(6):633-42 - PubMed
  35. JAMA. 2009 May 13;301(18):1883-91 - PubMed
  36. Curr Opin Clin Nutr Metab Care. 2003 Jan;6(1):87-93 - PubMed
  37. J Gen Intern Med. 2006 Mar;21(3):267-75 - PubMed
  38. Oncol Nurs Forum. 2006 Nov 03;33(2):327-35 - PubMed
  39. Cancer. 2003 Feb 1;97(3):674-81 - PubMed
  40. Med Clin North Am. 2011 May;95(3):427-38, ix - PubMed
  41. Ann Behav Med. 1999 Spring;21(2):171-9 - PubMed
  42. Scand J Med Sci Sports. 2012 Dec;22(6):804-15 - PubMed
  43. Gerontology. 2007;53(5):298-305 - PubMed
  44. J Natl Cancer Inst. 2009 Sep 2;101(17):1206-15 - PubMed
  45. Am J Health Promot. 2011 Mar-Apr;25(4):237-43 - PubMed
  46. Phys Ther. 2007 May;87(5):525-35 - PubMed

Publication Types

Grant support