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Harbert MJ, Jett M, Appelbaum M, et al. Perinatal risk factors and later social, thought, and attention problems after perinatal stroke. Stroke Res Treat. 2012;2012:914546doi: 10.1155/2012/914546.
Harbert, M. J., Jett, M., Appelbaum, M., Nass, R., & Trauner, D. A. (2012). Perinatal risk factors and later social, thought, and attention problems after perinatal stroke. Stroke research and treatment, 2012914546. https://doi.org/10.1155/2012/914546
Harbert, Mary J, et al. "Perinatal risk factors and later social, thought, and attention problems after perinatal stroke." Stroke research and treatment vol. 2012 (2012): 914546. doi: https://doi.org/10.1155/2012/914546
Harbert MJ, Jett M, Appelbaum M, Nass R, Trauner DA. Perinatal risk factors and later social, thought, and attention problems after perinatal stroke. Stroke Res Treat. 2012;2012:914546. doi: 10.1155/2012/914546. Epub 2012 May 20. PMID: 22685688; PMCID: PMC3364013.
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Stroke Res Treat. 2012;2012:914546. doi: 10.1155/2012/914546. Epub 2012 May 20.

Perinatal risk factors and later social, thought, and attention problems after perinatal stroke.

Stroke research and treatment

Mary J Harbert, Micaela Jett, Mark Appelbaum, Ruth Nass, Doris A Trauner

Affiliations

  1. Department of Neurosciences, University of California San Diego School of Medicine and Rady Children's Hospital-San Diego, La Jolla, CA 92093, USA.

PMID: 22685688 PMCID: PMC3364013 DOI: 10.1155/2012/914546

Abstract

Objective. Survivors of perinatal stroke may be at risk for behavioral problems. Perinatal risk factors that might increase the likelihood of later behavior problems have not been identified. The goal of this study was to explore whether perinatal factors might contribute to behavior problems after perinatal stroke. Methods. 79 children with unilateral perinatal stroke were studied. Perinatal factors included gender, gestational age, neonatal seizures, instrumented delivery, fetal distress, acute birth problems, birth weight, and time of diagnosis. Subjects with evidence of hypoxic ischemic encephalopathy were excluded. Parents completed the Achenbach Child Behavior Checklist (CBCL) (Achenbach 1985). The CBCL yields T-scores in several symptom scales. We focused on Social, Thought, and Attention Problems scates. Results. Gestational age and the presence of uteroplacental insufficiency were associated with significant differences on the Thought Problems scale; Attention Problems scores approached significance for these variables. Fetal distress, neonatal seizures, or neonatal diagnosis was associated with 25-30% incidence of clinically significant T-scores on Social, Thought, and Attention Problems scales. Conclusions. Several perinatal factors were associated with a high incidence of social, thought, and behavior problems in children with perinatal stroke. These findings may be useful in anticipatory guidance to parents and physicians caring for these children.

References

  1. Laterality. 1997;2(2):103-15 - PubMed
  2. Ann Neurol. 2005 Aug;58(2):303-8 - PubMed
  3. J Child Psychol Psychiatry. 1998 Mar;39(3):347-54 - PubMed
  4. J Int Neuropsychol Soc. 2004 Nov;10(7):976-86 - PubMed
  5. J Dev Behav Pediatr. 1990 Feb;11(1):1-6 - PubMed
  6. Pediatr Neurol. 1993 Sep-Oct;9(5):383-6 - PubMed
  7. Dev Med Child Neurol. 1995 Feb;37(2):109-18 - PubMed
  8. BMJ. 1996 Apr 27;312(7038):1065-9 - PubMed
  9. Arch Gen Psychiatry. 2011 Dec;68(12):1267-75 - PubMed
  10. Pediatr Neurol. 2008 Feb;38(2):118-25 - PubMed
  11. Arch Neurol. 1983 Aug;40(8):461-2 - PubMed
  12. Pediatrics. 2002 Jan;109(1):116-23 - PubMed
  13. J Int Neuropsychol Soc. 2004 Sep;10(5):698-708 - PubMed
  14. Brain. 2001 May;124(Pt 5):995-1002 - PubMed
  15. Cortex. 2007 Aug;43(6):792-805 - PubMed
  16. Acta Paediatr. 2011 Jul;100(7):992-9 - PubMed
  17. Curr Opin Pediatr. 2001 Dec;13(6):499-505 - PubMed
  18. Arch Neurol. 1983 Aug;40(8):463-8 - PubMed

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