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Prager W, Huber-Vorländer J, Taufig AZ, et al. Botulinum toxin type A treatment to the upper face: retrospective analysis of daily practice. Clin Cosmet Investig Dermatol. 2012;5:53-8doi: 10.2147/CCID.S26550.
Prager, W., Huber-Vorländer, J., Taufig, A. Z., Imhof, M., Kühne, U., Weissberg, R., Kuhr, L. P., Rippmann, V., Philipp-Dormston, W. G., Proebstle, T. M., Roth, C., Kerscher, M., Ulmann, C., & Pavicic, T. (2012). Botulinum toxin type A treatment to the upper face: retrospective analysis of daily practice. Clinical, cosmetic and investigational dermatology, 553-8. https://doi.org/10.2147/CCID.S26550
Prager, Welf, et al. "Botulinum toxin type A treatment to the upper face: retrospective analysis of daily practice." Clinical, cosmetic and investigational dermatology vol. 5 (2012): 53-8. doi: https://doi.org/10.2147/CCID.S26550
Prager W, Huber-Vorländer J, Taufig AZ, Imhof M, Kühne U, Weissberg R, Kuhr LP, Rippmann V, Philipp-Dormston WG, Proebstle TM, Roth C, Kerscher M, Ulmann C, Pavicic T. Botulinum toxin type A treatment to the upper face: retrospective analysis of daily practice. Clin Cosmet Investig Dermatol. 2012;5:53-8. doi: 10.2147/CCID.S26550. Epub 2012 Jun 08. PMID: 22791996; PMCID: PMC3393118.
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Clin Cosmet Investig Dermatol. 2012;5:53-8. doi: 10.2147/CCID.S26550. Epub 2012 Jun 08.

Botulinum toxin type A treatment to the upper face: retrospective analysis of daily practice.

Clinical, cosmetic and investigational dermatology

Welf Prager, Jürgen Huber-Vorländer, A Ziah Taufig, Matthias Imhof, Ulrich Kühne, Ruth Weissberg, Lars-Peter Kuhr, Volker Rippmann, Wolfgang G Philipp-Dormston, Thomas M Proebstle, Claudia Roth, Martina Kerscher, Claudius Ulmann, Tatjana Pavicic

Affiliations

  1. Dermatologikum, Hamburg.

PMID: 22791996 PMCID: PMC3393118 DOI: 10.2147/CCID.S26550

Abstract

BACKGROUND: Botulinum toxin type A treatment has been used for over 20 years to enhance the appearance of the face. There are several commercially available botulinum toxin type A products used in aesthetic clinical practice. The aim of this retrospective analysis was to compare the clinical efficacy of the most commonly used botulinum toxin type A preparations in daily practice.

METHODS: Physicians from 21 centers in Germany completed questionnaires based on an inspection of subject files for subjects 18 years of age or over who had received at least two, but not more than three, consecutive treatments with incobotulinumtoxinA, onabotulinumtoxinA, or abobotulinumtoxinA within a 12-month period in the previous 2 years. Data on subject and physician satisfaction, treatment intervals, dosages, and safety were collected from 1256 subjects.

RESULTS: There were no statistically significant differences between incobotulinumtoxinA and onabotulinumtoxinA with respect to physician and subject satisfaction, dosages, and adverse effects experienced. Both botulinum toxin type A preparations were well tolerated and effective in the treatment of upper facial lines. Due to low treatment numbers, abobotulinumtoxinA was not included in the statistical analysis.

CONCLUSION: The results of this retrospective analysis confirm the results of prospective clinical trials by demonstrating that, in daily practice, incobotulinumtoxinA and onabotulinumtoxinA are used at a 1:1 dose ratio and display comparable efficacy and safety.

Keywords: NT 201; abobotulinumtoxinA; incobotulinumtoxinA; onabotulinumtoxinA; retrospective analysis; upper face

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