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Iwamoto K, Kurata A, Suzuki S, et al. Pathophysiological evaluation of cerecyte coil embolization for experimental broad neck aneurysms. ISRN Neurol. 2012;2012:137873doi: 10.5402/2012/137873.
Iwamoto, K., Kurata, A., Suzuki, S., Ohmomo, T., Nakayama, S., Maruyama, S., Takagi, M., Konno, S., Nakahara, K., Fujii, K., Yasui, Y., & Iwabuchi, K. (2012). Pathophysiological evaluation of cerecyte coil embolization for experimental broad neck aneurysms. ISRN neurology, 2012137873. https://doi.org/10.5402/2012/137873
Iwamoto, Kazuhisa, et al. "Pathophysiological evaluation of cerecyte coil embolization for experimental broad neck aneurysms." ISRN neurology vol. 2012 (2012): 137873. doi: https://doi.org/10.5402/2012/137873
Iwamoto K, Kurata A, Suzuki S, Ohmomo T, Nakayama S, Maruyama S, Takagi M, Konno S, Nakahara K, Fujii K, Yasui Y, Iwabuchi K. Pathophysiological evaluation of cerecyte coil embolization for experimental broad neck aneurysms. ISRN Neurol. 2012;2012:137873. doi: 10.5402/2012/137873. Epub 2012 Jun 26. PMID: 22792483; PMCID: PMC3390053.
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ISRN Neurol. 2012;2012:137873. doi: 10.5402/2012/137873. Epub 2012 Jun 26.

Pathophysiological evaluation of cerecyte coil embolization for experimental broad neck aneurysms.

ISRN neurology

Kazuhisa Iwamoto, Akira Kurata, Sachio Suzuki, Taketomo Ohmomo, Shigenobu Nakayama, Shigeyoshi Maruyama, Mamoru Takagi, Shingo Konno, Kuniaki Nakahara, Kiyotaka Fujii, Yoshie Yasui, Keiichi Iwabuchi

Affiliations

  1. Department of Neurosurgery, Kitasato University School of Medicine, 1-15-1 Kitasato, Minami-ku, Kangawa, Sagamihara 228, Japan.

PMID: 22792483 PMCID: PMC3390053 DOI: 10.5402/2012/137873

Abstract

Cerecyte second-generation coils feature inner surfaces coated with an absorbable polyglycolic acid (PGA) polymer. Their use is expected to accelerate aneurysm organization, but time course data are limited. The present experimental study was therefore conducted to clarify the processes by pathological examination. Methods. Two types of experimental aneurysms were initially generated in adult mongrel dogs, one bifurcation and another of lateral wall type. Long-term persistence of each was defined by follow-up angiography for more than 1 year. Embolization of the aneurysms was then performed using only cerecyte coils, and follow-up angiography was conducted after 2 and 4 weeks followed by pathological examination. Results. Organization of both types of broad neck aneurysm was apparent 4 weeks after embolization, which is earlier as compared with already reported data for bare coils.

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