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J Chir (Paris). 2008 Oct;145(5):454-8. doi: 10.1016/S0021-7697(08)74655-6. Epub 2009 Jan 28.

[Not Available].

Journal de chirurgie

[Article in French]
A Delarue, C Bergeron, F Mechinaud-Lacroix, C Coze, M Raphael, C Patte, Pour le Comité Lymphome de la Sfce

Affiliations

  1. Service de chirurgie pédiatrique, hôpital d'enfants de la Timone - Marseille.

PMID: 22793520 DOI: 10.1016/S0021-7697(08)74655-6

Abstract

A. Delarue, C. Bergeron, F. Mechinaud-Lacroix, C. Coze, M. Raphael, C. Patte, pour le « Comité Lymphome » de la SFCE Over the past two decades, dramatic improvements in the treatment of children with Non-Hodgkin's Lymphoma have led to cure rates close to 90%, even in advanced-stage disease. The most frequent localization is abdominal, where Burkitt or Burkitt-like subtypes are predominant. Initial management often occurs in the setting of a urgent surgical intervention where multiple complications may gravely threaten prognosis within days or even hours. The SFCE Lymphoma Committee's guidelines for optimal management include: 1) The diagnosis of lymphoma should be systematically evoked whenever the clinical context is not consistent with idiopathic intussusception, particularly in children over the age of 3 or when clinical and/or ultrasound findings are not typical; 2) Limited bowel resection should be performed only if it allows complete tumor removal and is technically simple without extensive dissection or risk of major complications; 3) If surgical resection is likely to be difficult, risky, or incomplete, surgery should be limited to sampling of peritoneal fluid and tumor; 4) In all cases, adequate tissue should be obtained and sent to the pathology department in appropriate media Analysis of tumor material may require, in addition to histology and cytology, immunophenotyping, cytogenetics, and molecular biology studies in order to arrive at an accurate diagnosis and prognosis and to guide treatment choices.

Copyright © 2008 Elsevier Masson SAS. All rights reserved.

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