Cell. 2012 Aug 03;150(3):453-4. doi: 10.1016/j.cell.2012.07.015.
Cell
Jean-François Noël, Raymund J Wellinger
PMID: 22863000 DOI: 10.1016/j.cell.2012.07.015
In order for telomeres to remain functional and stable, they must rendezvous with the enzyme telomerase in a productive manner. In human cells, this interaction is mediated by Cajal bodies as matchmaker, and now Zhong et al. reveal molecular determinants that establish good chemistry between the two partners.
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