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Dionísio M, Grenha A. Locust bean gum: Exploring its potential for biopharmaceutical applications. J Pharm Bioallied Sci. 2012;4(3):175-85doi: 10.4103/0975-7406.99013.
Dionísio, M., & Grenha, A. (2012). Locust bean gum: Exploring its potential for biopharmaceutical applications. Journal of pharmacy & bioallied sciences, 4(3), 175-85. https://doi.org/10.4103/0975-7406.99013
Dionísio, Marita, and Grenha, Ana. "Locust bean gum: Exploring its potential for biopharmaceutical applications." Journal of pharmacy & bioallied sciences vol. 4,3 (2012): 175-85. doi: https://doi.org/10.4103/0975-7406.99013
Dionísio M, Grenha A. Locust bean gum: Exploring its potential for biopharmaceutical applications. J Pharm Bioallied Sci. 2012 Jul;4(3):175-85. doi: 10.4103/0975-7406.99013. PMID: 22923958; PMCID: PMC3425165.
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J Pharm Bioallied Sci. 2012 Jul;4(3):175-85. doi: 10.4103/0975-7406.99013.

Locust bean gum: Exploring its potential for biopharmaceutical applications.

Journal of pharmacy & bioallied sciences

Marita Dionísio, Ana Grenha

Affiliations

  1. CBME - Centre for Molecular and Structural Biomedicine/IBB - Institute for Biotechnology and Bioengineering, Faculty of Sciences and Technology, University of Algarve, Campus de Gambelas, Faro, Portugal.

PMID: 22923958 PMCID: PMC3425165 DOI: 10.4103/0975-7406.99013

Abstract

Polysaccharides have been finding, in the last decades, very interesting and useful applications in the biomedical and, specifically, in the biopharmaceutical field. Locust bean gum is a polysaccharide belonging to the group of galactomannans, being extracted from the seeds of the carob tree (Ceratonia siliqua). This polymer displays a number of appealing characteristics for biopharmaceutical applications, among which its high gelling capacity should be highlighted. In this review, we describe critical aspects of locust bean gum, contributing for its role in biopharmaceutical applications. Physicochemical properties, as well as strong and effective synergies with other biomaterials are described. The potential for in vivo biodegradation is explored and the specific biopharmaceutical applications are discussed.

Keywords: Controlled release; gelling capacity; locust bean gum; polysaccharides; synergy

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