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Indian J Clin Biochem. 2011 Oct;26(4):360-5. doi: 10.1007/s12291-011-0145-z. Epub 2011 Jul 15.

Efficacy of a fish protein hydrolysate in malnourished children.

Indian journal of clinical biochemistry : IJCB

Knut Olav Nesse, A P Nagalakshmi, P Marimuthu, Mamta Singh

Affiliations

  1. Zymtech Production AS, Lesja, Norway.

PMID: 23024471 PMCID: PMC3210250 DOI: 10.1007/s12291-011-0145-z

Abstract

UNLABELLED: Protein hydrolysates are good nutritional supplements as their bioactive ingredients can be easily absorbed and utilized for various metabolic activities. A fish protein hydrolysate (Amizate), prepared by a unique process of hydrolysis has the advantage of high di/tri peptide content (<10 kDa) along with essential and non essential amino acids, micronutrients and vitamins. The effect of Amizate on malnourished children (6-8 years, a total of 438) of Grade I and II (Gomez's classification) with respect to immunoglobulins, CD4/CD8 ratios and hemoglobin was examined. Measurement of these parameters during the user trial study (at the beginning and the end after 4 months) indicated that the levels of the immunological parameters were not significantly altered by the Amizate treatment. The values of immunoglobulins and CD4/CD8 ratios of malnourished children (India) are in the normal range and are in accordance with the reported values of various ethnic groups.

ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (doi:10.1007/s12291-011-0145-z) contains supplementary material, which is available to authorized users.

Keywords: Immunoglobulin; Malnourishment; Nutrition; Protein hydrolysates

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