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Del Prete A, Scalera A, Iadevaia MD, et al. Herbal products: benefits, limits, and applications in chronic liver disease. Evid Based Complement Alternat Med. 2012;2012:837939doi: 10.1155/2012/837939.
Del Prete, A., Scalera, A., Iadevaia, M. D., Miranda, A., Zulli, C., Gaeta, L., Tuccillo, C., Federico, A., & Loguercio, C. (2012). Herbal products: benefits, limits, and applications in chronic liver disease. Evidence-based complementary and alternative medicine : eCAM, 2012837939. https://doi.org/10.1155/2012/837939
Del Prete, Anna, et al. "Herbal products: benefits, limits, and applications in chronic liver disease." Evidence-based complementary and alternative medicine : eCAM vol. 2012 (2012): 837939. doi: https://doi.org/10.1155/2012/837939
Del Prete A, Scalera A, Iadevaia MD, Miranda A, Zulli C, Gaeta L, Tuccillo C, Federico A, Loguercio C. Herbal products: benefits, limits, and applications in chronic liver disease. Evid Based Complement Alternat Med. 2012;2012:837939. doi: 10.1155/2012/837939. Epub 2012 Sep 06. PMID: 22991573; PMCID: PMC3443820.
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Evid Based Complement Alternat Med. 2012;2012:837939. doi: 10.1155/2012/837939. Epub 2012 Sep 06.

Herbal products: benefits, limits, and applications in chronic liver disease.

Evidence-based complementary and alternative medicine : eCAM

Anna Del Prete, Antonella Scalera, Maddalena Diana Iadevaia, Agnese Miranda, Claudio Zulli, Laura Gaeta, Concetta Tuccillo, Alessandro Federico, Carmelina Loguercio

Affiliations

  1. Department of Clinical and Experimental Medicine, Interuniversity Research Centre on Food, Nutrition and the Gastrointestinal Tract (CIRANAD), 2nd University of Naples, 80131 Naples, Italy.

PMID: 22991573 PMCID: PMC3443820 DOI: 10.1155/2012/837939

Abstract

Complementary and alternative medicine soughts and encompasses a wide range of approaches; its use begun in ancient China at the time of Xia dynasty and in India during the Vedic period, but thanks to its long-lasting curative effect, easy availability, natural way of healing, and poor side-effects it is gaining importance throughout the world in clinical practice. We conducted a review describing the effects and the limits of using herbal products in chronic liver disease, focusing our attention on those most known, such as quercetin or curcumin. We tried to describe their pharmacokinetics, biological properties, and their beneficial effects (as antioxidant role) in metabolic, alcoholic, and viral hepatitis (considering that oxidative stress is the common pathway of chronic liver diseases of different etiology). The main limit of applicability of CAM comes from the lacking of randomized, placebo-controlled clinical trials giving a real proof of efficacy of those products, so that anecdotal success and personal experience are frequently the driving force for acceptance of CAM in the population.

References

  1. JAMA. 1998 Nov 11;280(18):1569-75 - PubMed
  2. Phytother Res. 2011 Nov;25(11):1721-6 - PubMed
  3. Zhonghua Gan Zang Bing Za Zhi. 2011 Jun;19(6):454-9 - PubMed
  4. J Agric Food Chem. 2011 Jul 27;59(14):7726-33 - PubMed
  5. Hepatology. 1999 Oct;30(4):1099-104 - PubMed
  6. Cancer Lett. 2007 Oct 8;255(2):170-81 - PubMed
  7. World J Gastroenterol. 2003 Jan;9(1):73-8 - PubMed
  8. Trends Mol Med. 2007 Aug;13(8):353-61 - PubMed
  9. Mol Nutr Food Res. 2011 Dec;55(12):1829-40 - PubMed
  10. Hepatology. 2010 Jun;51(6):1912-21 - PubMed
  11. Hepatology. 2001 Sep;34(3):595-603 - PubMed
  12. Antiviral Res. 2005 Nov;68(2):75-83 - PubMed
  13. Asian Pac J Trop Med. 2011 Jun;4(6):466-9 - PubMed
  14. Am J Physiol Gastrointest Liver Physiol. 2010 Nov;299(5):G1068-77 - PubMed
  15. J Ethnopharmacol. 2010 Jul 20;130(2):315-9 - PubMed
  16. Mol Cell Biochem. 2008 Aug;315(1-2):9-15 - PubMed
  17. Braz J Med Biol Res. 2007 Dec;40(12):1637-46 - PubMed
  18. Nutr Cancer. 2006;55(2):201-9 - PubMed
  19. Toxicol Mech Methods. 2010 Jun;20(5):252-9 - PubMed
  20. Lab Invest. 2010 Jan;90(1):104-15 - PubMed
  21. Can J Gastroenterol. 2007 Sep;21(9):589-95 - PubMed
  22. Mol Nutr Food Res. 2011 Apr;55(4):530-40 - PubMed
  23. Am J Chin Med. 2002;30(4):637-43 - PubMed
  24. Hepatology. 2006 Apr;43(4):796-806 - PubMed
  25. Arch Intern Med. 1998 Nov 9;158(20):2200-11 - PubMed
  26. J Hepatol. 1994 Oct;21(4):601-9 - PubMed
  27. J Ethnopharmacol. 2008 Jun 19;118(1):1-6 - PubMed
  28. Food Chem Toxicol. 2010 May;48(5):1145-51 - PubMed
  29. J Gastroenterol Hepatol. 1999 Nov;14(11):1093-9 - PubMed
  30. Br J Pharmacol. 2009 Aug;157(8):1352-3 - PubMed
  31. Gastroenterology. 2010 Feb;138(2):671-81, 681.e1-2 - PubMed
  32. FEBS Lett. 2010 Jun 3;584(11):2485-90 - PubMed
  33. Arch Pharm Res. 2012 Jan;35(1):77-85 - PubMed
  34. J Hepatol. 2006 Oct;45(4):539-46 - PubMed
  35. J Ethnopharmacol. 2010 Mar 24;128(2):549-53 - PubMed
  36. Dig Dis Sci. 2006 Mar;51(3):603-9 - PubMed
  37. Fitoterapia. 2010 Oct;81(7):799-802 - PubMed
  38. Curr Opin Clin Nutr Metab Care. 1999 Sep;2(5):421-4 - PubMed
  39. Planta Med. 2010 Aug;76(11):1118-31 - PubMed
  40. Altern Med Rev. 2011 Sep;16(3):239-49 - PubMed
  41. Biol Pharm Bull. 2004 Feb;27(2):251-5 - PubMed
  42. Acta Pol Pharm. 2009 Jul-Aug;66(4):439-44 - PubMed
  43. Molecules. 2012 Jan 12;17(1):716-27 - PubMed
  44. Aliment Pharmacol Ther. 1998 Mar;12(3):199-205 - PubMed
  45. J Chromatogr A. 2011 Nov 11;1218(45):8181-91 - PubMed
  46. Eur J Pharmacol. 2008 May 13;585(2-3):325-37 - PubMed
  47. Bioinformation. 2011 Feb 15;5(10):430-9 - PubMed
  48. J Viral Hepat. 2012 Feb;19(2):e81-8 - PubMed
  49. Biol Chem. 2010 Oct;391(10):1175-87 - PubMed
  50. Phytother Res. 2008 Feb;22(2):141-8 - PubMed
  51. Support Care Cancer. 2009 Mar;17(3):231-40 - PubMed
  52. J Ethnopharmacol. 2007 Sep 25;113(3):503-9 - PubMed
  53. Pharmacogn Mag. 2011 Jul;7(27):229-33 - PubMed
  54. Mol Cell Biochem. 2010 Jan;333(1-2):41-8 - PubMed
  55. J Soc Integr Oncol. 2007 Spring;5(2):65-84 - PubMed
  56. Zhong Xi Yi Jie He Xue Bao. 2011 Jan;9(1):49-56 - PubMed
  57. Biosci Trends. 2010 Apr;4(2):39-47 - PubMed
  58. J Gastroenterol Hepatol. 1997 Mar;12(3):243-8 - PubMed
  59. J Ethnopharmacol. 2008 Mar 5;116(2):333-40 - PubMed
  60. J Gastroenterol Hepatol. 2002 Dec;17 Suppl 3:S370-6 - PubMed
  61. Integr Cancer Ther. 2011 Dec;10(4):NP4-14 - PubMed
  62. Cancer. 1995 Sep 1;76(5):743-9 - PubMed
  63. J Pharmacol Exp Ther. 2011 Oct;339(1):93-8 - PubMed
  64. Cancer Treat Rev. 2010 Apr;36(2):157-63 - PubMed
  65. J Res Med Sci. 2011 Mar;16(3):287-90 - PubMed
  66. Eur J Nutr. 2011 Apr;50(3):163-72 - PubMed
  67. Clin Gastroenterol Hepatol. 2004 Nov;2(11):947-56 - PubMed
  68. Virol Sin. 2010 Oct;25(5):375-80 - PubMed
  69. Food Funct. 2012 Feb;3(2):101-9 - PubMed
  70. Immunol Lett. 1992 Apr;32(2):147-52 - PubMed
  71. J Hepatol. 2005 Nov;43(5):901-10 - PubMed
  72. Nutr Cancer. 2009;61(5):735-45 - PubMed
  73. Int J Pharm. 2007 Feb 7;330(1-2):155-63 - PubMed
  74. Am J Chin Med. 2010;38(2):343-58 - PubMed
  75. J Clin Pharm Ther. 2002 Dec;27(6):391-401 - PubMed
  76. J Med Food. 2010 Dec;13(6):1485-9 - PubMed
  77. Virus Res. 2011 Jun;158(1-2):89-97 - PubMed
  78. Food Funct. 2011 Jan;2(1):11-7 - PubMed
  79. Mol Pharm. 2007 Nov-Dec;4(6):807-18 - PubMed
  80. J Biomed Biotechnol. 2009;2009:981963 - PubMed
  81. Eur J Cancer Prev. 2011 May;20(3):225-39 - PubMed
  82. Med Clin (Barc). 2004 Mar 13;122(9):334-5 - PubMed
  83. Hepatology. 2010 May;51(5):1555-66 - PubMed
  84. World J Gastroenterol. 2008 Mar 14;14(10):1491-7 - PubMed
  85. J Med Food. 2009 Apr;12(2):327-33 - PubMed
  86. Life Sci. 2008 Oct 10;83(15-16):531-9 - PubMed
  87. Phytother Res. 2010 Sep;24(9):1405-13 - PubMed
  88. Nutr Metab (Lond). 2011 Mar 28;8(1):18 - PubMed
  89. Hepatology. 2008 Feb;47(2):605-12 - PubMed
  90. Biochem J. 2009 Jul 15;421(3):473-82 - PubMed
  91. Toxicol Mech Methods. 2011 Jan;21(1):48-52 - PubMed
  92. Drug Saf. 1997 Nov;17(5):342-56 - PubMed
  93. Indian J Med Res. 2009 May;129(5):569-78 - PubMed
  94. JAMA. 1998 May 20;279(19):1548-53 - PubMed
  95. Asian Pac J Trop Med. 2011 Jun;4(6):470-4 - PubMed
  96. J Ethnopharmacol. 2010 Jul 20;130(2):208-15 - PubMed
  97. Drug Metab Dispos. 2008 Jul;36(7):1438-43 - PubMed
  98. Nutrition. 2008 Jul-Aug;24(7-8):703-10 - PubMed
  99. Exp Mol Pathol. 2011 Jun;90(3):295-9 - PubMed
  100. Indian J Biochem Biophys. 2010 Feb;47(1):20-5 - PubMed
  101. Cochrane Database Syst Rev. 2011 Apr 13;(4):CD008960 - PubMed
  102. Arch Surg. 2003 Aug;138(8):852-8 - PubMed
  103. Am J Clin Nutr. 2007 Jul;86(1):14-24 - PubMed
  104. Alcohol Clin Exp Res. 2006 Mar;30(3):407-13 - PubMed
  105. Scand J Gastroenterol. 2006 Sep;41(9):1087-94 - PubMed
  106. World J Gastroenterol. 2012 Feb 21;18(7):679-84 - PubMed
  107. J Ethnopharmacol. 2010 Mar 2;128(1):172-6 - PubMed
  108. J Ethnopharmacol. 2011 Nov 18;138(2):286-313 - PubMed
  109. World J Gastroenterol. 2011 Aug 28;17(32):3663-4 - PubMed
  110. Food Chem Toxicol. 2012 May;50(5):1194-200 - PubMed
  111. Am J Physiol Gastrointest Liver Physiol. 2007 Oct;293(4):G894-902 - PubMed
  112. Indian J Clin Biochem. 2010 Oct;25(4):419-24 - PubMed
  113. Curr Oncol. 2008 Jan;15(1):42-8 - PubMed
  114. Food Chem Toxicol. 2010 Aug-Sep;48(8-9):2170-5 - PubMed
  115. J Ethnopharmacol. 2007 Nov 1;114(2):169-73 - PubMed
  116. Z Naturforsch C J Biosci. 2011 Sep-Oct;66(9-10):447-52 - PubMed
  117. Gastroenterol Clin Biol. 2007 Apr;31(4):415-20 - PubMed
  118. J Nutr. 2011 Jul;141(7):1299-305 - PubMed
  119. FEBS Lett. 2010 Feb 19;584(4):707-12 - PubMed
  120. Eksp Klin Gastroenterol. 2011;(2):130-5 - PubMed
  121. Phytother Res. 2010 Feb;24(2):189-92 - PubMed
  122. J Ethnopharmacol. 2011 Jan 27;133(2):765-72 - PubMed
  123. Chemistry. 2012 Feb 6;18(6):1650-8 - PubMed
  124. Biochem J. 2005 Nov 15;392(Pt 1):191-9 - PubMed
  125. Pharm Biol. 2011 Oct;49(10):995-1007 - PubMed
  126. Toxicol In Vitro. 2010 Mar;24(2):516-22 - PubMed
  127. Eur J Clin Invest. 1996 Dec;26(12):1069-76 - PubMed
  128. J Hepatol. 2004 Mar;40(3):491-500 - PubMed
  129. Phytomedicine. 2005 Sep;12(9):619-24 - PubMed
  130. Phytomedicine. 2008 Dec;15(12):1053-61 - PubMed
  131. Virol J. 2011 Apr 01;8:153 - PubMed
  132. Med Princ Pract. 2012;21(1):24-9 - PubMed
  133. Planta Med. 1997 Dec;63(6):518-24 - PubMed
  134. Cancer Res. 2008 Mar 15;68(6):2033-42 - PubMed
  135. Int J Hepatol. 2012;2012:962183 - PubMed
  136. Inflamm Res. 2009 Sep;58(9):593-9 - PubMed
  137. Food Chem Toxicol. 2010 Jul;48(7):1863-8 - PubMed
  138. Am J Physiol Gastrointest Liver Physiol. 2010 May;298(5):G634-42 - PubMed
  139. Microcirculation. 2009 May;16(4):364-76 - PubMed
  140. J Gastroenterol Hepatol. 1992 Jan-Feb;7(1):12-6 - PubMed
  141. Eur J Clin Invest. 2009 Sep;39(9):761-8 - PubMed
  142. Dig Liver Dis. 2007 Apr;39(4):293-304 - PubMed
  143. Yakugaku Zasshi. 2000 Oct;120(10):849-62 - PubMed
  144. Biotherapy. 1992;5(3):167-76 - PubMed
  145. Alcohol Clin Exp Res. 2006 Jan;30(1):76-85 - PubMed
  146. J Lipid Res. 2010 Nov;51(11):3158-65 - PubMed
  147. Hepatology. 2008 Jun;47(6):1905-15 - PubMed
  148. J Med Assoc Thai. 1991 Sep;74(9):381-5 - PubMed
  149. Dig Dis Sci. 2007 Sep;52(9):2387-95 - PubMed
  150. Dig Dis Sci. 2005 Oct;50(10):1807-12 - PubMed
  151. J Ethnopharmacol. 2011 Oct 11;137(3):1337-44 - PubMed
  152. Orv Hetil. 2009 Jan 11;150(2):73-9 - PubMed
  153. J Ayurveda Integr Med. 2010 Jul;1(3):203-10 - PubMed
  154. Nat Prod Commun. 2010 Dec;5(12):1935-8 - PubMed
  155. Liver Int. 2011 Apr;31(4):552-60 - PubMed
  156. J Ayub Med Coll Abbottabad. 2009 Oct-Dec;21(4):73-5 - PubMed
  157. Food Chem Toxicol. 2008 Aug;46(8):2658-64 - PubMed
  158. Inflammopharmacology. 2012 Dec;20(6):331-41 - PubMed
  159. Inflammopharmacology. 2011 Aug;19(4):235-41 - PubMed
  160. Biol Pharm Bull. 2008 Apr;31(4):743-7 - PubMed
  161. Chang Gung Med J. 2010 Sep-Oct;33(5):477-87 - PubMed
  162. J Ethnopharmacol. 1995 Jan;45(1):1-18 - PubMed
  163. Arzneimittelforschung. 2005;55(10):561-8 - PubMed
  164. Med Sci Monit. 2012 Jan;18(1):BR24-32 - PubMed
  165. J Gastroenterol Hepatol. 2001 Dec;16(12):1329-35 - PubMed
  166. Oncol Rep. 2011 Mar;25(3):609-17 - PubMed
  167. J Transl Med. 2011 Jul 18;9:112 - PubMed
  168. Int Immunopharmacol. 2012 Mar;12(3):518-25 - PubMed

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