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Romão W, Sabino BD, Bueno MI, et al. LSD and 9,10-dihydro-LSD analyses in street drug blotter samples via easy ambient sonic-spray ionization mass spectrometry (EASI-MS). J Forensic Sci. 2012;57(5):1307-12doi: 10.1111/j.1556-4029.2012.02237.x.
Romão, W., Sabino, B. D., Bueno, M. I., Vaz, B. G., Júnior, A. C., Maldaner, A. O., de Castro, E. V., Lordeiro, R. A., Nascentes, C. C., Eberlin, M. N., & Augusti, R. (2012). LSD and 9,10-dihydro-LSD analyses in street drug blotter samples via easy ambient sonic-spray ionization mass spectrometry (EASI-MS). Journal of forensic sciences, 57(5), 1307-12. https://doi.org/10.1111/j.1556-4029.2012.02237.x
Romão, Wanderson, et al. "LSD and 9,10-dihydro-LSD analyses in street drug blotter samples via easy ambient sonic-spray ionization mass spectrometry (EASI-MS)." Journal of forensic sciences vol. 57,5 (2012): 1307-12. doi: https://doi.org/10.1111/j.1556-4029.2012.02237.x
Romão W, Sabino BD, Bueno MI, Vaz BG, Júnior AC, Maldaner AO, de Castro EV, Lordeiro RA, Nascentes CC, Eberlin MN, Augusti R. LSD and 9,10-dihydro-LSD analyses in street drug blotter samples via easy ambient sonic-spray ionization mass spectrometry (EASI-MS). J Forensic Sci. 2012 Sep;57(5):1307-12. doi: 10.1111/j.1556-4029.2012.02237.x. Epub 2012 Aug 06. PMID: 22880936.
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J Forensic Sci. 2012 Sep;57(5):1307-12. doi: 10.1111/j.1556-4029.2012.02237.x. Epub 2012 Aug 06.

LSD and 9,10-dihydro-LSD analyses in street drug blotter samples via easy ambient sonic-spray ionization mass spectrometry (EASI-MS).

Journal of forensic sciences

Wanderson Romão, Bruno D Sabino, Maria Izabel M S Bueno, Boniek G Vaz, Amadeu C Júnior, Adriano O Maldaner, Eustáquio V R de Castro, Rogério A Lordeiro, Clésia C Nascentes, Marcos N Eberlin, Rodinei Augusti

Affiliations

  1. ThoMSon Mass Spectrometry Laboratory, Institute of Chemistry, State University of Campinas-UNICAMP, Campinas, SP, Brazil. [email protected]

PMID: 22880936 DOI: 10.1111/j.1556-4029.2012.02237.x

Abstract

Normally, the identification of the LSD drug is performed by forensic laboratories, using the Ehrlich spot test. However, this is a nonspecific analysis. Additionally, the Brazilian Federal Police has identified the presence of a new compound in seized blotters: 9,10-dihydro-LSD, an uncontrolled substance. In this work, easy ambient sonic-spray ionization mass spectrometry in the positive ion mode, EASI(+)-MS, was used to characterize LSD and 9,10-dihydro-LSD compositions directly from the surface of blotters. The presence of LSD in the seized blotter samples were also confirmed via high-performance liquid chromatography with ultraviolet detector. In a set of 41 blotters analyzed by EASI(+)-MS, 28 showed positive results for LSD, seven for 9,10-dihydro-LSD, and another six samples showed negative results for both LSD and 9,10-dihydro-LSD. The combination of thin layer chromatography with EASI-MS also demonstrated to be a relatively simple and powerful screening tool for forensic analysis of street drugs.

© 2012 American Academy of Forensic Sciences.

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