Display options
Share it on

Crit Care Res Pract. 2012;2012:437659. doi: 10.1155/2012/437659. Epub 2012 Oct 04.

Extravascular lung water does not increase in hypovolemic patients after a fluid-loading protocol guided by the stroke volume variation.

Critical care research and practice

Carlos Ferrando, Gerardo Aguilar, F Javier Belda

Affiliations

  1. Department of Anesthesiology and Critical Care, Hospital ClĂ­nico Universitario de Valencia, 46010 Valencia, Spain.

PMID: 23091710 PMCID: PMC3471432 DOI: 10.1155/2012/437659

Abstract

Introduction. Circulatory failure secondary to hypovolemia is a common situation in critical care patients. Volume replacement is the first option for the treatment of hypovolemia. A possible complication of volume loading is pulmonary edema, quantified at the bedside by the measurement of extravascular lung water index (ELWI). ELWI predicts progression to acute lung injury (ALI) in patients with risk factors for developing it. The aim of this study was to assess whether fluid loading guided by the stroke volume variation (SVV), in patients presumed to be hypovolemic, increased ELWI or not. Methods. Prospective study of 17 consecutive postoperative, fully mechanically ventilated patients diagnosed with circulatory failure secondary to presumed hypovolemia were included. Cardiac index (CI), ELWI, SVV, and global end-diastolic volume index (GEDI) were determined using the transpulmonary thermodilution technique during the first 12 hours after fluid loading. Volume replacement was done with a strict hemodynamic protocol. Results. Fluid loading produced a significant increase in CI and a decrease in SVV. ELWI did not increase. No correlation was found between the amount of fluids administered and the change in ELWI. Conclusion. Fluid loading guided by SVV in hypovolemic and fully mechanically ventilated patients in sinus rhythm does not increase ELWI.

References

  1. Crit Care Med. 2003 May;31(5):1399-404 - PubMed
  2. Eur J Anaesthesiol. 2006 Jan;23(1):36-41 - PubMed
  3. Anaesthesist. 1989 Jul;38(7):360-74 - PubMed
  4. Intensive Care Med. 2003 Mar;29(3):352-60 - PubMed
  5. Neth J Med. 2000 Sep;57(3):82-93 - PubMed
  6. Anesth Analg. 2001 Apr;92(4):984-9 - PubMed
  7. Curr Opin Crit Care. 2007 Oct;13(5):549-53 - PubMed
  8. Intensive Care Med. 2005 Apr;31(4):517-23 - PubMed
  9. Am J Respir Crit Care Med. 2000 Jul;162(1):134-8 - PubMed
  10. Br J Anaesth. 2005 Jun;94(6):721-6 - PubMed
  11. Chest. 2002 Jun;121(6):2000-8 - PubMed
  12. Anesthesiology. 2005 Aug;103(2):419-28; quiz 449-5 - PubMed
  13. Crit Care Med. 2005 Oct;33(10):2339-43 - PubMed
  14. Surgery. 1986 Feb;99(2):140-53 - PubMed
  15. Acta Anaesthesiol Scand. 2004 Jan;48(1):69-73 - PubMed
  16. Crit Care Med. 2012 Mar;40(3):793-9 - PubMed
  17. Curr Opin Crit Care. 2006 Jun;12(3):235-40 - PubMed
  18. Chest. 2002 Jun;121(6):1956-62 - PubMed
  19. Chest. 2005 Aug;128(2):848-54 - PubMed
  20. Crit Care. 2010;14(4):R142 - PubMed
  21. Crit Care Med. 2008 Jun;36(6):1803-9 - PubMed
  22. Br J Anaesth. 2012 Mar;108(3):395-401 - PubMed
  23. Eur J Anaesthesiol. 2005 Sep;22(9):658-65 - PubMed
  24. Crit Care Med. 2012 Mar;40(3):847-54 - PubMed
  25. Can J Physiol Pharmacol. 1986 Apr;64(4):383-7 - PubMed
  26. Intensive Care Med. 2002 Apr;28(4):392-8 - PubMed
  27. Anesthesiology. 1998 Dec;89(6):1313-21 - PubMed
  28. Crit Care Med. 2009 Apr;37(4):1275-81 - PubMed
  29. Crit Care Med. 2008 Oct;36(10):2810-6 - PubMed
  30. Crit Care. 2000;4(5):282-9 - PubMed
  31. Anesth Analg. 2003 May;96(5):1254-1257 - PubMed
  32. Intensive Care Med. 2006 Jul;32(7):1030-8 - PubMed
  33. Crit Care Med. 2010 Jan;38(1):114-20 - PubMed
  34. Am J Physiol. 1985 Apr;248(4 Pt 2):H468-76 - PubMed

Publication Types