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Edwards C, Rogers A, Lynch S, et al. The effects of bariatric surgery weight loss on knee pain in patients with osteoarthritis of the knee. Arthritis. 2012;2012:504189doi: 10.1155/2012/504189.
Edwards, C., Rogers, A., Lynch, S., Pylawka, T., Silvis, M., Chinchilli, V., Mosher, T., & Black, K. (2012). The effects of bariatric surgery weight loss on knee pain in patients with osteoarthritis of the knee. Arthritis, 2012504189. https://doi.org/10.1155/2012/504189
Edwards, Christopher, et al. "The effects of bariatric surgery weight loss on knee pain in patients with osteoarthritis of the knee." Arthritis vol. 2012 (2012): 504189. doi: https://doi.org/10.1155/2012/504189
Edwards C, Rogers A, Lynch S, Pylawka T, Silvis M, Chinchilli V, Mosher T, Black K. The effects of bariatric surgery weight loss on knee pain in patients with osteoarthritis of the knee. Arthritis. 2012;2012:504189. doi: 10.1155/2012/504189. Epub 2012 Dec 03. PMID: 23243506; PMCID: PMC3518076.
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Arthritis. 2012;2012:504189. doi: 10.1155/2012/504189. Epub 2012 Dec 03.

The effects of bariatric surgery weight loss on knee pain in patients with osteoarthritis of the knee.

Arthritis

Christopher Edwards, Ann Rogers, Scott Lynch, Tamara Pylawka, Matthew Silvis, Vernon Chinchilli, Timothy Mosher, Kevin Black

Affiliations

  1. Penn State College of Medicine, Penn State Hershey Medical Center, Penn State University, 500 University Drive, Hershey, PA 17033, USA.

PMID: 23243506 PMCID: PMC3518076 DOI: 10.1155/2012/504189

Abstract

Studies have shown that osteoarthritis (OA) is highly associated with obesity, and individuals clinically defined as obese (BMI > 30.0 kg/m(2)) are four times more likely to have knee OA over the general population. The purpose of this research was to examine if isolated weight loss improved knee symptoms in patients with osteoarthritis. Adult patients (n = 24; age 18-70; BMI > 35 kg/m(2)) with clinical and radiographic evidence of knee OA participated in a one-year trial in which WOMAC and KOOS surveys were administered at a presurgery baseline and six and twelve months postsurgery. Statistical analysis was performed using Student's t and Wilcoxon Signed Rank tests. Weight loss six and twelve months following bariatric surgery was statistically significant (P < 0.05) compared to presurgery measurements. All variables from both KOOS and WOMAC assessments were significantly improved (P < 0.05) when compared to baseline. Isolated weight loss occurring via bariatric surgery resulted in statistically significant improvement in patient's knee arthritis symptoms at both six and twelve months. Further research will need to be done to determine if symptom relief continues over time, and if the benefits are also applicable to individuals with symptomatic knee arthritis that are overweight but not obese.

References

  1. NCHS Data Brief. 2007 Nov;(1):1-8 - PubMed
  2. Obesity (Silver Spring). 2006 Jul;14(7):1219-30 - PubMed
  3. AJR Am J Roentgenol. 2006 Sep;187(3):794-9 - PubMed
  4. J Rheumatol. 1988 Dec;15(12):1833-40 - PubMed
  5. Aliment Pharmacol Ther. 1997 Apr;11(2):283-91 - PubMed
  6. J Am Acad Orthop Surg. 2000 Sep-Oct;8(5):277-84 - PubMed
  7. Osteoarthritis Cartilage. 2005 Jan;13(1):20-7 - PubMed
  8. Arthritis Rheum. 2004 May;50(5):1501-10 - PubMed
  9. J Bone Joint Surg Am. 2007 Apr;89(4):780-5 - PubMed
  10. Arch Intern Med. 2005 Mar 14;165(5):490-6 - PubMed
  11. Ann Rheum Dis. 2001 Sep;60(9):834-40 - PubMed
  12. Arthritis Rheum. 2009 Dec;60(12):3546-53 - PubMed
  13. Cochrane Database Syst Rev. 2006 Apr 19;(2):CD005321 - PubMed
  14. Am J Ther. 2004 Jan-Feb;11(1):17-25 - PubMed
  15. Osteoarthritis Cartilage. 2010 Apr;18(4):476-99 - PubMed
  16. Clin Orthop Relat Res. 2006 May;446:22-8 - PubMed
  17. J Cardiovasc Pharmacol. 2006;47 Suppl 1:S60-6 - PubMed
  18. Arch Intern Med. 2009 Jun 22;169(12):1113-21; discussion 1121-2 - PubMed
  19. Arthritis Rheum. 2008 Jan;58(1):15-25 - PubMed
  20. Int J Obes (Lond). 2007 Jan;31(1):114-20 - PubMed
  21. N Engl J Med. 2002 Jul 11;347(2):81-8 - PubMed
  22. Health Qual Life Outcomes. 2003 May 25;1:17 - PubMed
  23. Curr Pharm Des. 2002;8(12):1063-75 - PubMed
  24. Pain. 2003 Aug;104(3):549-557 - PubMed

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