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Grekova SP, Rommelaere J, Raykov Z. Parvoviruses-tools to fine-tune anticancer immune responses. Oncoimmunology. 2012;1(8):1417-1419doi: 10.4161/onci.21097.
Grekova, S. P., Rommelaere, J., & Raykov, Z. (2012). Parvoviruses-tools to fine-tune anticancer immune responses. Oncoimmunology, 1(8), 1417-1419. https://doi.org/10.4161/onci.21097
Grekova, Svitlana P, et al. "Parvoviruses-tools to fine-tune anticancer immune responses." Oncoimmunology vol. 1,8 (2012): 1417-1419. doi: https://doi.org/10.4161/onci.21097
Grekova SP, Rommelaere J, Raykov Z. Parvoviruses-tools to fine-tune anticancer immune responses. Oncoimmunology. 2012 Nov 01;1(8):1417-1419. doi: 10.4161/onci.21097. PMID: 23243613; PMCID: PMC3518522.
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Oncoimmunology. 2012 Nov 01;1(8):1417-1419. doi: 10.4161/onci.21097.

Parvoviruses-tools to fine-tune anticancer immune responses.

Oncoimmunology

Svitlana P Grekova, Jean Rommelaere, Zahari Raykov

Affiliations

  1. Programme Infection and Cancer; Tumour Virology Division F010 and Institut National de la Santé et de la Recherche Médicale (INSERM; Unit 701; German Cancer Research Center (DKFZ); Heidelberg, Germany.

PMID: 23243613 PMCID: PMC3518522 DOI: 10.4161/onci.21097

Abstract

Oncolytic virotherapy represents a recent approach to anticancer therapy. Rodent autonomous parvoviruses (PVs) represent naturally oncolytic viruses that are non-pathogenic for humans but possess and extended tropism, being capable of infecting transformed cells of both rodent and human origin. Recent work from our group demonstrate that PVs can act as direct lytic agents and adjuvants, stimulating antitumor immune responses against glioma and pancreatic ductal adenocarcinoma (PDAC).

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