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Int J Trichology. 2012 Jul;4(3):169-71. doi: 10.4103/0974-7753.100085.

Hodgkin's Lymphoma Presenting as Alopecia.

International journal of trichology

Sunny Garg, Sourav Mishra, Ravi Tondon, Kamlakar Tripathi

Affiliations

  1. Department of General Medicine, Institute of Medical Sciences, Banaras Hindu University, Varanasi, Uttar Pradesh, India.

PMID: 23180928 PMCID: PMC3500058 DOI: 10.4103/0974-7753.100085

Abstract

Alopecia is a rare manifestation of Hodgkin's disease. It may be due to follicular destruction due to direct infiltration by the disease, or it may be a secondary or paraneoplastic manifestation. In this patient, hair loss, diffuse yperpigmentation, and generalized itching preceded other manifestations of the disease. The pattern of hair loss was diffuse and generalized in nature involving scalp, eyebrows, axilla, and groin. Subsequently, the patient was diagnosed to be a case of Hodgkin's lymphoma, based on clinical and histopathological features. Earlier reports on alopecia accompanying Hodgkin's disease have also been discussed. This case highlights the importance of keeping a high suspicion of an underlying malignancy in patients presenting with such cutaneous manifestations.

Keywords: Alopecia; Hodgkin's disease; paraneoplastic

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