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Int J Trichology. 2012 Jul;4(3):176-8. doi: 10.4103/0974-7753.100090.

N-acetylcysteine in the Treatment of Trichotillomania.

International journal of trichology

Ana Rita Rodrigues-Barata, Antonella Tosti, Antonio Rodríguez-Pichardo, Francisco Camacho-Martínez

Affiliations

  1. Department of Dermatology and Venereology, Hospital Universitario Virgen Macarena, Seville, Spain.

PMID: 23180931 PMCID: PMC3500061 DOI: 10.4103/0974-7753.100090

Abstract

Trichotillomania is as medical condition caused by the patient himself by pulling out of is own hair, resulting in a perceptible hair loss pattern that frequently is associated with other psychiatric processes. Generally has a chronic course in most patients, and a challenging therapeutical management. There are several available options for is treatment, but the clinical response is not satisfactory in many patients. Recently, N-acetylcisteine, a glutamate modulator, has shown efficacy in the treatment of trichotillomania and other compulsive behaviors, and is considered a new alternative in the management of this condition. We describe two patients with trichotillomania successfully treated with N-acetylcysteine. Nevertheless, further studies need to be conducted to establish the appropriate treatment regimen and to evaluate it long-term efficacy in improving this chronic condition.

Keywords: Compulsive behavior; N-acetylcysteine; treatment; trichotillomania

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