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Indian J Clin Biochem. 2001 Jan;16(1):110-2. doi: 10.1007/BF02867578.

Differential erythrocyte agglutination pattern in normal and cancer patients with Synadenium grantii root (Hook f) lectin.

Indian journal of clinical biochemistry : IJCB

P P Durgawale, P S Shukla, S D Sontakke, P G Chougule

Affiliations

  1. Dept of Biochemistry, Krishna Institute of Medical Sciences, 415110 Karad.

PMID: 23105302 PMCID: PMC3453605 DOI: 10.1007/BF02867578

Abstract

In the present study the property of lectin agglutination in blood on normal and different cancer patients has been observed. The purifiedSynadenium grantii root lectin was non blood group specific and its utility as a diagnostic tool in malignancy was studied. Hemagglutination (units/ml) of red blood cells of different types of cancer was compared with the normal control's red blood cells. Out of 113 total cancer patients, only a group of 29 breast cancer patients showed significant increase in titre value (P<0.05) compared to normal control.

Keywords: Cancer Hemagglutination; Lectin; Red cell membrane

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